Gastric Antral Vascular Ectasia
Conditions
Keywords
GAVE, G.A.V.E, Gastric Antral Vascular, Gastric Antral Vascular Ectasia
Brief summary
The purpose of this research is to determine whether a procedure called capillaroscopy can help distinguish patients who are diagnosed with GAVE (gastric antral vascular ectasia) with an autoimmune disease versus idiopathic/other conditions based on EGD findings.
Detailed description
The primary aim of this study is to define the prevalence and findings (as per quantification) of nail fold video capillaroscopy abnormalities in patients with GAVE. The secondary aim is to compare the findings of NVC and clinical presentation in patients with GAVE.
Interventions
DEVICEVideo Capillaroscopy
A non-invasive imaging technique used to assess capillary structure and morphology in the nailfold area, commonly used in evaluating microvascular changes associated with connective tissue diseases.
Sponsors
Mayo Clinic
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
* Patients 18 years and older with gave diagnosis as pair EGD performed in Gastroenterology as standard of care. Patients with GAVE with connective tissue disease will be compared to patients with GAVE without a connective tissue disease.
Exclusion criteria
* Age less than 18 years of age, pregnant individuals, dialysis dependent, type 2 diabetes, recent hand trauma or manicure (\<2 weeks), routine use of vibratory tools, history of acrocyanosis or erythromelalgia, previous diagnosis of a bleeding disorder, diagnosis of psoriasis, diagnosis of anti-phospholipid syndrome, exposure to toluene or benzoyl, diagnosis of psoriasis, diagnosis of COPD.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence and Phenotypic with G.A.V.E | From enrollment to end of study once the accrual has been met within baseline of Day 1 | Defined the prevalence and phenotype of nail fold video capillaroscopy abnormalities in patients with G.A.V.E. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comparing Findings | From enrollment to end of study once the accrual has been met within baseline of day 1 | To compare the findings of and VC and clinical manifestation and organ involvement patients with gave and connective tissue disease to those with gave without connective tissue disease. |
Countries
United States
Contacts
PRINCIPAL_INVESTIGATORFlorentina Berianu, M.D.
Mayo Clinic
Outcome results
None listed