Absorbable, Coated Sutures, Closure Technique, Dermatology, Mohs Micrographic Surgery, Suture, Suture Dermatologic, Suture Techniques
Conditions
Keywords
Petrolatum, Absorbable Suture, Gut Suture, Fast-absorbing Gut Suture, Wound Closure, Suture Coating
Brief summary
This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the suture. Two gut sutures were placed into the skin of 14 healthy volunteers and randomized between coated and uncoated with petrolatum. Participants self-reported the time to resorption. The study concluded that there was no significant effect to the application of petrolatum, and reinforced that the gut sutures are a natural product with some inherent variability to their absorption.
Interventions
6-0 fast absorbing gut suture was coated with sterile petrolatum and a single interrupted suture was placed into the skin of the deltoid
Sponsors
Study design
Eligibility
Inclusion criteria
* Healthy volunteers within department of Dermatology * Able to receive care within the host facility (Dept of Defense)
Exclusion criteria
* current or planned pregnancy * Allergy to lidocaine * Infection on the shoulder site
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Length of time that suture remains intact in skin following petrolatum coating compared with standard fast-absorbing gut suture. | Postprocedurally daily until suture is degraded (less than 2 weeks) | Length of time in hours of suture remaining in skin prior to breakdown was recorded for both uncoated and coated suture. |