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Effect of Petrolatum Coating on Fast-absorbing Gut Suture

Effect Of Petrolatum On Absorption of Fast Gut Suture In Vivo

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07127029
Enrollment
14
Registered
2025-08-17
Start date
2016-01-26
Completion date
2016-10-14
Last updated
2025-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Absorbable, Coated Sutures, Closure Technique, Dermatology, Mohs Micrographic Surgery, Suture, Suture Dermatologic, Suture Techniques

Keywords

Petrolatum, Absorbable Suture, Gut Suture, Fast-absorbing Gut Suture, Wound Closure, Suture Coating

Brief summary

This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the suture. Two gut sutures were placed into the skin of 14 healthy volunteers and randomized between coated and uncoated with petrolatum. Participants self-reported the time to resorption. The study concluded that there was no significant effect to the application of petrolatum, and reinforced that the gut sutures are a natural product with some inherent variability to their absorption.

Interventions

DEVICEPetrolatum coating of fast-absorbing gut suture

6-0 fast absorbing gut suture was coated with sterile petrolatum and a single interrupted suture was placed into the skin of the deltoid

Sponsors

San Antonio Uniformed Services Health Education Consortium
Lead SponsorFED

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Healthy volunteers within department of Dermatology * Able to receive care within the host facility (Dept of Defense)

Exclusion criteria

* current or planned pregnancy * Allergy to lidocaine * Infection on the shoulder site

Design outcomes

Primary

MeasureTime frameDescription
Length of time that suture remains intact in skin following petrolatum coating compared with standard fast-absorbing gut suture.Postprocedurally daily until suture is degraded (less than 2 weeks)Length of time in hours of suture remaining in skin prior to breakdown was recorded for both uncoated and coated suture.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026