Post-ERCP Pancreatitis
Conditions
Keywords
Endoscopic retrograde cholangiopancreatography, ERCP complications, Pancreatitis risk factors
Brief summary
This study was conducted at the Department of Gastroenterology, Lady Reading Hospital, Peshawar, Pakistan, from January 2023 to December 2023. It aimed to determine how often patients develop pancreatitis (inflammation of the pancreas) after undergoing a procedure called endoscopic retrograde cholangiopancreatography (ERCP), and to identify the main factors that increase this risk. We reviewed the medical records of 300 adult patients who had ERCP for various conditions, such as bile duct stones, tumors, and strictures. We assessed patient characteristics, procedure details, and laboratory results to see which factors were linked to post-ERCP pancreatitis. The study found that prolonged cannulation time, injection of contrast into the pancreatic duct, and high levels of C-reactive protein before the procedure were the strongest predictors of this complication. These findings may help doctors identify high-risk patients and take preventive steps to reduce the chances of pancreatitis after ERCP.
Interventions
PROCEDUREObservational study
This is an observational study with no experimental or therapeutic interventions administered to participants. All data were collected retrospectively from existing hospital records for patients who underwent ERCP between January 2023 and December 2023 at Lady Reading Hospital, Peshawar. No drugs, devices, or procedures were assigned to participants as part of this research.
Sponsors
Nangarhar University
Study design
Observational model
OTHER
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Known chronic pancreatitis * Pancreatic malignancy * Pre-existing acute pancreatitis * Incomplete procedural or laboratory records
Exclusion criteria
* Known chronic pancreatitis * Pancreatic malignancy * Pre-existing acute pancreatitis * Incomplete procedural or laboratory records
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of Post-ERCP Pancreatitis | Within 24 hours after ERCP and during hospitalization | The number and proportion of patients developing post-ERCP pancreatitis (PEP), defined as new or worsened abdominal pain with serum amylase or lipase levels ≥3 times the upper limit of normal within 24 hours after ERCP, requiring hospitalization or prolongation of hospital stay. |
Countries
Pakistan
Outcome results
None listed