Edentulous Alveolar Ridge
Conditions
Brief summary
This study aims to conduct a cross-sectional study to compare the differences in clinical indices, patient-reported outcomes, and levels of inflammatory factors in peri-implant gingival crevicular fluid between sites with adequate (≥ 2 mm) and inadequate (\< 2 mm) keratinized mucosa after implant restoration, in order to explore the impact of the presence of keratinized mucosa on peri-implant soft and hard tissue health.
Interventions
OTHERNo intervention
No intervention: observational case-control study
Sponsors
The Dental Hospital of Zhejiang University School of Medicine
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Individuals aged 18 to 70 years (inclusive of 18 and 70 years), of any gender; * Patients who have undergone dental implant restoration是（single crown or fixed bridge restorations） at the Stomatology Hospital, Zhejiang University School of medicine and have had their final restoration for at least 6 months; * Patients who voluntarily participate and sign the informed consent form after being fully informed, and who cooperate with relevant examinations.
Exclusion criteria
* Patients who are unwilling to participate in the follow-up of this study for various reasons
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Width of Keratinized Mucosa, KMW | on the day of enrollment | — |
| Plaque Index(PI) | on the day of enrollment | — |
| Bleeding on Probing(BOP) | on the day of enrollment | — |
| Peri-implant Probing Depth(PPD) | on the day of enrollment | — |
| Marginal Bone Loss(MBL) | The X-ray examination will be completed on the day of enrollment | — |
| Patient Satisfaction | on the day of enrollment | visual analogue scale \[VAS\] 0-10,e.g., not at all satisfied to perfectly satisfied |
| Immunological parameters in peri-implant crevicular fluids(PICF) | The PICF will be collected on the day of enrollment | PICF samples were collected from buccal aspects of implants after removing all supragingival plaque. The levels of IL-1β and PGE2 in PICF were measured using a sandwich ELISA kit. |
Countries
China
Contacts
Primary ContactMisi Si
Outcome results
None listed