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Impact of Point-of-care Lactate Testing as Triage Supplement on Patient Management Using Manchester Triage System

Impact of Point-of-care Lactate Testing as Triage Supplement on Patient Management Using Manchester Triage System

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07123857
Enrollment
200
Registered
2025-08-14
Start date
2025-07-10
Completion date
2026-12-31
Last updated
2025-08-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emergency Department Overcrowding, Emergency Department Triage, Emergency Medicine, Triage

Brief summary

Although the Manchester Triage System (MTS) is widely used and validated internationally, it has some limitations. Its accuracy is moderate, especially for children and the elderly. Rising patient numbers and overcrowded emergency departments increase wait times, sometimes beyond safe limits. In Slovenia, MTS has been in use for 14 years without major updates, despite a significant rise in emergency visits. The yellow triage category (60-minute wait time) includes a very diverse group of patients, some of whom might require faster care. Older patients, in particular, often show atypical symptoms and may be under-triaged. Including rapid bedside lab tests, like blood lactate levels, could improve risk assessment and triage accuracy. Elevated lactate is linked with higher mortality and can help identify critically ill patients more effectively. The proposed study is a prospective, randomized trial involving two groups of patients in the yellow triage category, all of whom will have their capillary blood lactate levels measured. Patients with normal lactate levels will be excluded. Only patients with elevated lactate will be compared. The test group will be re-triaged to the orange category and treated more urgently. The control group, despite also having high lactate levels, will remain in the yellow category, and their elevated lactate values will not be shared with the treating physician. Randomization will be based on the patient's birth date (even days = test group, odd days = control group). Only the nurse will know the result, maintaining physician blinding to avoid the Hawthorne effect-changes in behavior due to awareness of being studied. Standard lab tests will be performed later during treatment as deemed necessary by the attending doctor.

Interventions

DIAGNOSTIC_TESTre-triage

Patients in the test group will be re-triaged into the orange MTS category.

Sponsors

University Medical Centre Maribor
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* signed consent, yellow MTS triage category

Exclusion criteria

* pregnant women, trauma patients, epileptic seizures, adrenergic therapy in prehospital unit

Design outcomes

Primary

MeasureTime frame
Vasoactive drug use30-day

Secondary

MeasureTime frame
In-hospital mortality30-day
ICU admission30-day

Countries

Slovenia

Contacts

Primary ContactJerica Zaloznik Djordjevic, MD
jerica.zalo@gmail.com00386 31 696 858

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026