Acute Ischemic Stroke, Arterial Occlusion Disease, Posterior Circulation Brain Infarction
Conditions
Brief summary
Posterior circulation strokes (PCS) represent \ 30% of all ischemic strokes, but existing prognostic tools are limited, especially for non-basilar artery occlusions. Accurate early outcome prediction may aid treatment decisions and clinical trial design. We developed and externally validated the Posterior Circulation Clot Burden Score (PC-CBS), a radiological tool to predict 3-month functional outcome in acute ischemic stroke due to posterior circulation occlusion.
Interventions
DIAGNOSTIC_TESTAssessment of cervico-cerebral arterial occlusion pattern
Assessment of cervico-cerebral arterial occlusion pattern for the development of a radiological score
Sponsors
Insel Gruppe AG, University Hospital Bern
Hospital de Egas Moniz
University Hospital Heidelberg
IRCCS Istituto delle Scienze Neurologiche di Bologna
The University of Texas Health Science Center, Houston
Azienda Ospedaliero-Universitaria di Modena
Hospital Vall d'Hebron
Boston University
Università degli Studi di Brescia
Medical University of Graz
Hôpital Rothschild
Medical University of Vienna
Hebrew University of Jerusalem
Michigan State University
Medical University Innsbruck
Ludwig-Maximilians - University of Munich
Ospedale Policlinico San Martino
EOC Lugano CH
University Hospital, Basel, Switzerland
Aristotle University Of Thessaloniki
Technische Universität Dresden
Centre Hospitalier Universitaire Vaudois
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age \>18 years old * admitted within 24h from last known well * symptomatic arterial occlusion. The following arterial occlusions were eligible for inclusion: the extracranial vertebral artery between the V0 and V3 segments; the intracranial portion of the vertebral artery; the basilar artery either in its proximal, mid and/or distal segment, the P1 and/or the P2 segments of the posterior cerebral artery.
Exclusion criteria
* simultaneous clinical and/or radiological strokes in the posterior and anterior circulation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified rankin scale at three months | 3 months |
Outcome results
None listed