Apnea, Body Mass Index, Oxygen Reserve Index, Ventilation
Conditions
Brief summary
Background: The Oxygen Reserve Index (ORI) is a non-invasive parameter utilizing multi-wavelength pulse co-oximetry. ORI can provide early warnings of deteriorating oxygenation before changes are reflected in SpO₂ levels. This study aimed to investigate the feasibility of non-ventilated intubation in patients undergoing cholecystectomy as a means to achieve safe intubation without nasogastric tube placement, with reduced trauma and cost, and improved time efficiency.
Detailed description
Obesity is a complex and chronic disease that significantly impacts respiratory physiology. It leads to increased work of breathing and reduced compliance of the chest wall. In morbidly obese individuals, there is a marked reduction in total lung capacity, vital capacity, forced expiratory volume in one second (FEV1), and forced vital capacity (FVC). Additionally, due to their elevated metabolic demands, these patients exhibit higher oxygen consumption rates. The Oxygen Reserve Index (ORi) (Masimo Corp., Irvine, CA, USA) is an advanced, continuous, and non-invasive parameter that provides a relative indication of arterial partial pressure of oxygen (PaO₂). ORI monitoring can be particularly beneficial in patients at risk for inadequate preoxygenation, those with difficult mask ventilation, hypoxemic patients with aspiration risk, rapid sequence induction scenarios, obese individuals, ICU intubations, and invasive ventilation cases. It has also been shown to provide early warnings of desaturation in select patient groups, contributing to improved patient safety.
Interventions
OTHEROXYGEN RESERVE INDEX
Noted for each patient.
Sponsors
Ankara City Hospital Bilkent
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* 18-60 years * ASA 1-2 * Mallampati score \<2 * Scheduled for elective laparoscopic cholecystectomy under general anesthesia
Exclusion criteria
* \<18 and \>60 years * ASA 3-4 * Initial ORI value below 0.24
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| TIME FOR ORI TO FALL BELOW 0.24 | WITHIN 10 MINUTES BEFORE INTUBATION | TIME THE PATIENT STARTED TO WEAR A MASKS. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| ORI VALUE AT 2 MINUTES | WITHIN 10 MINUTES BEFORE INTUBATION | Noted for each patient. |
| AGE | WITHIN 10 MINUTES BEFORE INTUBATION | Noted for each patient. |
| American Society of Anesthesiologists (ASA) Score | WITHIN 10 MINUTES BEFORE INTUBATION | Noted for each patient. |
| SEX | WITHIN 10 MINUTES BEFORE INTUBATION | Noted for each patient. |
| INITIAL ORI VALUE | WITHIN 10 MINUTES BEFORE INTUBATION | Noted for each patient. |
| PRESENCE OF A NASOGASTRIC TUBE | 10 MINUTES BEFORE EXTUBATION | Noted for each patient. |
| Surgeon satisfaction | 10 MINUTES BEFORE EXTUBATION | Noted for each patient. Surgeon satisfaction according to ng usage status. |
| PRESENCE OF LARYNGOSPASM | 10 MINUTES BEFORE EXTUBATION | Noted for each patient. |
| BMI | WITHIN 10 MINUTES BEFORE INTUBATION | Noted for each patient. |
Countries
Turkey (Türkiye)
Contacts
Primary ContactAyşegül Özel Erdem
Backup ContactAyça Özcan
Outcome results
None listed