ERAS
Conditions
Brief summary
The goal of this clinical trial is to determine the length of hospital stay in patients using multimodal analgesia with or without ERAS protocol scheduled for elective laparoscopic gynecological surgeries
Interventions
DRUGEnhanced Recovery After Surgery
Preoperatively ERAS protocol includes, No solid food for 6 hours before procedure; 800 ml (fantomalt powder) Carbohydrate drink 8 hours before surgery; 400 ml (fantomalt powder) 2 hours before surgery; Celecoxib 200g 1 hour before surgery . Intraoperatively, on induction lidocaine 1.5 mg/kg and Fentanyl 1 to 2 mcg/kg followed by IV lidocaine infusion at 1.5 mg/kg/h.
DRUGControl
Preoperatively, NPO 6 hours before the procedure Intraoperatively, on induction Nabuphine 0.1mg/kg
Sponsors
Aga Khan University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* ASA physical status I, II, and III * Patients scheduled for elective laparoscopic gynecological surgeries
Exclusion criteria
* Refusal to participate * History of allergy or contraindication to study drugs * Patients in which procedure converted to open surgery * Diagnostic laparoscopic procedures * Patients with a history of severe anxiety or depression
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Length of hospital stay | From arrival in the recovery room post-surgery until 72 hours after surgery. | Post-operative length of hospital stay, measured in hours from the patient's arrival in the recovery room until 72 hours after surgery. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative pain score | 4 hours, 8 hours, 12 hours, 24 hours, 48 hours & 72 hours postoperatively | Post operative pain score will be measures using NRS (Numerical Rating Scale). Eleven points pain scale measures from 0-10, where "0" is no pain and "10" is the worst possible pain |
| Amount of opioid used in patient controlled analgesia | 12 hours postoperatively. | Total Nalbuphine consumption in 12 hours (in milligrams) |
| Patient satisfaction Score | 24 hours after the operation | Patient satisfaction with the pain management regimen will be assessed using a five-point Likert scale 24 hours after surgery. The scale ranges from 1 to 5, where 1 = Very Dissatisfied, 2 = Dissatisfied, 3 = Neutral, 4 = Satisfied, and 5 = Very Satisfied. Higher scores indicate greater satisfaction. |
Countries
Pakistan
Contacts
CONTACTAli Sarfraz Siddiqui, MBBS, MCPS, FCPS, FIPP, MHPE
Outcome results
None listed