No Prognostic or Molecular Disparity Between Synchronous and Metachronous Metastases in Differentiated Thyroid Cancer: Insight From Middle Eastern Cohort

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07115810

Enrollment

178

Registered

2025-08-11

Start date

1988-01-01

Completion date

2024-12-31

Last updated

2025-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Differentiated Thyroid Cancer

Keywords

synchronous metastasis, metachronous metastasis, prognosis

Brief summary

The goal of this observational study is to compare the clinical outcomes, molecular features, and immune profiles of patients with synchronous and metachronous distant metastases in Saudi cohort with well characterized differentiated thyroid cancer. The main question it aims to answer is whether timing of metastasis is associated with distinct prognostic or biological behavior in differentiated thyroid cancer from a large Middle Eastern cohort

Interventions

OTHERNo additional drugs(control Group)

No intervention

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Inclusion criteria

* Synchronous or metachronous distant metastases

Exclusion criteria

* Not DTC * No distant metastases

Design outcomes

Primary

Measure	Time frame
Overall survival	5 years

Secondary

Measure	Time frame
Thyroid cancer-specific survival	5 years

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026