Deep Brain Stimulation, Parkinson's Disease
Conditions
Keywords
deep brain stimulation, EEG, electric potential
Brief summary
To measure the electric fields induced by DBS (deep brain stimulation) on the scalp and to improve electric field simulations, the investigators will measure EEG (electroencephalography) measurements with high sampling rates (\>100 kHz). The investigators hypothesize that we can improve electric field simulations of DBS by validating and calibrating the simulations based on EEG measurements at high sampling rates (\>100 kHz).
Interventions
OTHEREEG recording
EEG will be recorded at high sampling rate
Sponsors
University of Twente
Universitätsklinikum Hamburg-Eppendorf
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
35 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Provision of written informed consent by the patient * Age 35 - 85 * patient groups: Parkinson's disease, essential tremor, dystonia * \>3 months after surgery for DBS
Exclusion criteria
none.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Electric potential at the EEG locations | during DBS | The investigators will extract the DBS pulses from the EEG data and check the distribution of the electric potentials as seen in simulations based on individual MRI and CT images. Parameters of the simulation pipeline (e.g. conductances) will be adjusted so that the simulation models fit the data. |
Countries
Germany
Contacts
Primary ContactBettina C. Schwab, PhD
Backup ContactThomas Keizers
Outcome results
None listed