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Effects Of Quadratus Lumborum Type 1 Block And Transversalis Facial Plane Block On Acute Pain In Gynecological Surgery

Effects Of Quadratus Lumborum Type 1 Block And Transversalis Facial Plane Block On Acute Pain In Gynecological Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07114965
Acronym
GYNQLBFPB
Enrollment
68
Registered
2025-08-11
Start date
2025-06-01
Completion date
2025-08-01
Last updated
2025-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecologic Surgery, Postoperative Pain

Brief summary

This study was conducted to evaluate the effectiveness of Quadratus Lumborum Type 1 and Transversalis Fascial Plane blocks on postoperative acute pain in gynecology operations.

Detailed description

In gynecological operations, especially total abdominal hysterectomy, moderate to severe postoperative pain is usually accompanied. Inadequately treated postoperative abdominal hysterectomy pain causes delayed postoperative recovery, prolonged hospital stay, chronic pain, increased chance of venous thrombosis and patient dissatisfaction. Multimodal analgesia techniques are widely used, but new evidence has shown that combinations with regional anesthesia techniques are the most effective method in postoperative pain treatment. Opioids continue to be the main step in postoperative pain treatment, despite strong evidence of their disadvantages. Opioid administration in acute postoperative pain is associated with many side effects such as sedation, pruritus, nausea and vomiting. Regional analgesia techniques used to reduce the amount of opioid used and provide effective analgesia are becoming an integral part of postoperative opioid-sparing analgesia. Open surgeries increase tissue trauma and increase inflammatory response due to high surgical stress. The reduction of pain by regional analgesia application facilitates postoperative mobilization and reduces complications. Abdominal wall blocks are performed on the principle of high-volume local anesthetic deposition within a fascial plane. Ultrasound-guided performance with continuous visualization of the needle improves placement accuracy and reduces inadvertent visceral or neurovascular injury. Abdominal wall blocks primarily provide somatic analgesia, but newer blocks can also block visceral nerves. Abdominal wall blocks provide a relatively safe alternative to epidural analgesia without the risk of motor block, hypotension, or central neuraxis. The quadratus lumborum fascial block (QLB), recently described by Blanco and modified by Sauter et al, is considered an extension of the TAP block. A local anesthetic is injected adjacent to the QL muscle, which aims to anesthetize the thoracolumbar nerves. The QL muscle is a quadrangular-shaped posterior abdominal wall muscle that inserts inferiorly on the iliac crest, cranially on the 12th rib, medially on the transverse processes of L1 to L4, and has a free lateral margin. The QL muscle is related to the PM muscle on its anterior surface and to the spinal erector muscle group on its posterior surface. The muscle is surrounded by the thoracolumbar fascia. Three techniques for QLB have been described and named according to the position of the needle tip in relation to the QL muscle: QLB type 1 or lateral; type 2 or posterior; and transmuscular, or anterior. Many case reports and randomized trials have included analgesia for gynecologic and lower abdominal surgery, Pfannenstiel incision for cesarean section, proctosigmoidectomy, hip surgery, abdominal hernioplasty, nephrectomy, and laparotomy as indications. There are several case reports with different indications for QLB for sensory block between T7 and L2. The transversalis fascial plane block is a truncal block that targets the L1 nerve branches, namely the ilioinguinal and iliohypogastric nerves. The ilioinguinal and iliohypogastric nerves originate from the lateral border of the psoas major muscle, below the 12th rib, and run along the anterior surface of the quadratus lumborum muscle. Lateral to the quadratus lumborum muscle, it initially descends deep to the transversus abdominis muscle for a variable distance and penetrates the transversus abdominis muscle to enter the transversus abdominis plane between the internal oblique and transversus abdominis muscles. This block is also an analgesic option for inguinal hernia repair, open appendectomy, and any surgical procedure involving the L1 dermatome. In this study, the investigators will evaluate the effectiveness of quadratus lumborum and transversalis fascial plane blocks, which are abdominal wall blocks, on postoperative acute pain in open gynecological operations.

Interventions

None listed

Sponsors

Ankara Diskapi Training and Research Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* ASA I-III * 18-80 years old women's medicines * Open myomectomy and total abdominal hysterectomy cases

Exclusion criteria

* Those who do not want a block * Patients who are allergic to local anesthetics * Patients with coagulopathy · * Pregnancy * Previous surgery in the area where the block will be applied

Design outcomes

Primary

MeasureTime frameDescription
Postoperative pain between groupsday 1The steps of expanding the transversalis fascial plane in acute pain are being investigated against the quadratus lumborum 1 spread applied in gynecological surgery.

Secondary

MeasureTime frameDescription
Time to first rescue analgesic consumptionday 1To investigate the effects of transversalis fascial plane block versus quadratus lumborum 1 block on the recovery time and the time to first postoperative analgesic consumption in patients undergoing gynecological surgery.
total opioid consumptionday 1Monitoring of total opioid consumption for 24 hours postoperatively

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026