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Enhancing Utility of Neuropsychological Evaluation for Earlier and Effective Diagnosis of Dementia in Parkinson's Disease

Enhancing Utility of Neuropsychological Evaluation for Earlier and Effective Diagnosis of Dementia in Parkinson's Disease

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07114354
Acronym
PDCogniCare
Enrollment
275
Registered
2025-08-11
Start date
2025-08-18
Completion date
2026-12-31
Last updated
2025-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dementia (Diagnosis), Parkinson Disease Dementia (PDD), Parkinson Disease (PD)

Keywords

Parkinson's disease, Dementia, Cognitive evaluation, Implementation

Brief summary

Dementia is observed in 80% of people living with advanced stage Parkinson's disease, however, there are inadequate opportunities for early and effective diagnosis of dementia in current clinical practice. This study aims to identify whether a new tool called PDCogniCare, can improve detection of dementia in people living with Parkinson's disease, and to explore what factors might influence its use in healthcare services.

Detailed description

The PDCogniCare tool integrates best practice guidelines for cognitive evaluations in people living with Parkinson's disease, along with a tailored digital platform to support guideline implementation and routinely track cognitive changes throughout the disease course. We hypothesize that PDCogniCare will significantly enhance cognitive evaluations within healthcare services. Embedded process and economics evaluations will inform implementation and sustainable business models of PDCogniCare.

Interventions

OTHERPDCogniCare platform

Digital platform designed to support early and accurate detection of dementia in people living with Parkinson's disease

Sponsors

Medical Research Future Fund
CollaboratorOTHER
Metro South Health
CollaboratorOTHER
Metro North Health
CollaboratorUNKNOWN
Queensland University of Technology
CollaboratorOTHER
University of Sydney
CollaboratorOTHER
OPN365
CollaboratorUNKNOWN
Australian Dementia Network
CollaboratorUNKNOWN
Dementia Australia
CollaboratorUNKNOWN
Lions Club of Brisbane Inner North
CollaboratorUNKNOWN
Parkinson's Queensland
CollaboratorUNKNOWN
The University of Queensland
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* People living with idiopathic Parkinson's disease, one year or more post-diagnosis, attending Movement Disorder Clinics

Exclusion criteria

* People with severe Parkinson's disease who aren't able to communicate * People with comorbid neurological conditions (e.g. Stroke)

Design outcomes

Primary

MeasureTime frame
Change in percentage of people with Parkinson's disease diagnosed with dementia12 months from enrolment

Secondary

MeasureTime frame
Change in percentage of people with Parkinson's disease diagnosed with mild cognitive impairment12 months from enrolment

Contacts

Primary ContactNadeeka Dissanayaka
pdcognicare@uq.edu.au+617 3346 5577
Backup ContactTiffany Au
dnmh@uq.edu.au

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026