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Fundus-First Laparoscopic Cholecystectomy in Difficult Gallbladders: A Safe Alternative Technique

Fundus-First Laparoscopic Cholecystectomy in Difficult Gallbladders: A Retrospective Cross-Sectional Study on a Safe Alternative to Avoid Conversion

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07113704
Enrollment
124
Registered
2025-08-11
Start date
2023-01-05
Completion date
2024-04-10
Last updated
2025-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholelithiasis

Keywords

fundus-first laparoscopic cholecystectomy, difficult cholecystectomy, Cross-sectional study, General surgery, Laparoscopic cholecystectomy, Tertiary care hospital

Brief summary

This retrospective cross-sectional study evaluated the safety and effectiveness of the fundus-first laparoscopic cholecystectomy (FFLC) technique in patients with difficult gallbladders. A total of 124 patients who underwent FFLC between 2023 and 2024 were reviewed. The study assessed operative time, intraoperative complications, conversion rates, and postoperative outcomes. The results suggest that FFLC is a safe and feasible approach that can reduce the need for conversion to open surgery in complex cases. The study was conducted at a private hospital in Istanbul, Turkey

Detailed description

This retrospective study was conducted at a private healthcare institution without a formal IRB. All patient data were anonymised before analysis, and written informed consent was obtained from all patients for the academic use of their clinical data

Interventions

PROCEDUREFundus-First Laparoscopic Cholecystectomy

Laparoscopic cholecystectomy technique initiated at the gallbladder fundus and carried out retrogradely toward Calot's triangle. This method was applied to difficult gallbladders (Nassar Grade 3-4) to improve operative safety and avoid conversion to open surgery.

Standard laparoscopic cholecystectomy technique starting at Calot's triangle. Used as the comparator group in this study.

Sponsors

KANAN ISMAYILZADA, MD
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients who underwent laparoscopic cholecystectomy at the study center between January 2023 and March 2024 * Patients diagnosed with difficult gallbladder (Nassar Grade 3-4) * Age ≥ 18 years * Complete clinical data available for analysis

Exclusion criteria

* Patients with incomplete medical records * Patients undergoing open cholecystectomy from the beginning * Patients under 18 years of age

Design outcomes

Primary

MeasureTime frameDescription
Conversion Rate to Open SurgeryIntraoperative (during surgery)Rate of conversion from laparoscopic to open cholecystectomy in each group. Measured as number and percentage of patients converted.

Secondary

MeasureTime frameDescription
Operative TimeIntraoperative (during surgery)Total operative time measured in minutes from skin incision to closure. Comparison between the fundus-first and conventional laparoscopic cholecystectomy groups.
Postoperative Complication RateWithin 30 days postoperativelyIncludes complications such as wound infection, bile leak, abscess, or any adverse event requiring medical or surgical intervention. Compared between groups
Length of Hospital StayPostoperative hospitalizationNumber of days from surgery to discharge. Mean values will be compared between groups.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026