Muscle Recovery
Conditions
Keywords
Protein, muscle recovery, Tea extract, EIMD
Brief summary
In this research project, we want to investigate whether the combined intake of proteins and tea extract has an influence on muscle regeneration compared to the sole intake of proteins or a placebo product. In the study, you will be randomly assigned to one of 3 groups. Neither the research group nor you will know which group you are assigned to. The study lasts 5 days for you as a participant. During these 5 days you will have to attend a total of 5 appointments in our laboratory. The groups differ only in the intake of the regeneration product, otherwise all measurements and appointments are identical. You will jog downhill for 30 minutes on the first day in order to strain your muscles. In order to be able to draw conclusions about the regeneration of your muscles, we will carry out the following measurements on all 5 days: Blood sampling at the fingertip, ultrasound of the thigh muscle, pain tolerance of the thigh muscle, strength tests of the thigh muscle, muscle function of the thigh muscle and jumping performance.
Interventions
DIETARY_SUPPLEMENTProtein and tea extract
Participants in this group will receive 4 times a recovery drink containing protein and tea extract.
DIETARY_SUPPLEMENTProtein
Participants of this group will receive ten times a recovery drink containing only protein without tea extract.
DIETARY_SUPPLEMENTPlacebo
Participants of this group will receive 10 times a placebo containing no protein nor tea extract.
Sponsors
University of Fribourg
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)
Intervention model description
randomized, double-blinded, placebo-controlled.
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Signed written informed consent * Aged between 18-40 years * Healthy subjects
Exclusion criteria
* Any type of food allergy (e.g. nuts) * Health-related problems according to the "Physical Activity Readiness Questionnaire (PAR-Q) * Current injury of the lower extremities * Serious clinical back pain or current back injuries * Orthopedic disorders * Cardiovascular diseases * Current Intake of blood-thinning medication * Current Intake of anti-inflammatory medication
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in maximum knee extension force immediately after training-induced muscle damage and 24, 48, 72, and 96 hours thereafter compared to baseline. | 5 days | The maximal force is measured in Nm while the participant is seated on an isokinetic device. |
| Change in jump performance immediately after training-induced muscle damage and 24, 48, 72, and 96 hours thereafter compared to baseline. | 5 days | The jump performance is measured in cm while the participant are performing counter movement jumps. |
| Change in perceived pain immediately after training-induced muscle damage and 24, 48, 72, and 96 hours thereafter compared to baseline. | 5 days | Perceived pain is measured in Pa while the participant is seated on the isokinetic device. The measurement point is on vastus medialis muscle. |
| Change in muscle thickness immediately after training-induced muscle damage and 24, 48, 72, and 96 hours thereafter compared to baseline. | 5 days | Muscle thickness is measured with b-mode ultrasound in mm while the participant is sitting on the isokinetic device. The measurement point is on the vastus medialis muscle. |
| Change in creatine kinase levels immediately after exercise-induced muscle damage and 24, 48, 72, and 96 hours thereafter compared to baseline. | 5 days | Creatine kinase is measured in U/L and determined using a capillary finger blood sample of 0.25 ml. |
Countries
Switzerland
Contacts
CONTACTSven Egger, Dr.
CONTACTBenedikt Lauber, PD Dr.
Outcome results
None listed