Malignant Bone Tumor
Conditions
Brief summary
The investigators will collect data of patients with high suspicion of malignant bone tumor based on radiological imaging who underwent/will undergo both core needle biopsy and incisional biopsy for diagnostic confirmation by histological examination. From 01/01/2015 to the approval date of this study: retrospective study; from the approval date of this study to 31/12/2027: prospective study. the investigators expect to collect data from a total of 72 patients: approximately 30 patients for the retrospective study and 42 for the prospective study. A review will be made from the medical records, radiological imaging, and histological data of partecipants.
Interventions
PROCEDUREincisional or core-needle biopsy for tumor diagnosis
incisional or core-needle biopsy for tumor diagnosis
Sponsors
Istituto Ortopedico Rizzoli
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
2 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥ 2 years * Patients with high suspicion of malignant bone tumor who underwent/will undergo both core needle biopsy and incisional biopsy * Male and female patients treated at Rizzoli Orthopaedic Institute from the approval date of this study to 31/12/2027 * Patients with available clinical and imaging data
Exclusion criteria
* Patients with bone tumor who underwent/will undergo only core needle biopsy * Patients with bone tumor who underwent/ will undergo only incisional biopsy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| compare the agreement between core needle biopsy and incisional biopsy, based on Cohen's kappa coefficient. | through study completion, an average of 3 year |
Countries
Italy
Outcome results
None listed