Acute Ischemic Stroke
Conditions
Keywords
Acute ischemic stroke, mechanical thrombectomy, dual stentriever, mTICI, first pass effect, randomized trial
Brief summary
This study seeks to provide high-quality evidence on the potential benefits of the dual stentriever approach, potentially informing future clinical guidelines and improving outcomes in patients with anterior circulation large vessel occlusion strokes.
Interventions
DEVICEdual sr
Dual Stentriever
DEVICEsingle sr
Single Stentriever
Sponsors
Instituto de Investigación Marqués de Valdecilla
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Intervention model description
Endovascular mechanical thrombectomy with either dual or single stentriever technique using a balloon guiding catheter.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥ 18 * NIHSS ≥ 6 * mRS ≤ 1 * Proximal anterior circulation occlusion * ASPECTS \> 6 * Informed consent
Exclusion criteria
* Absence of occlusion * Posterior circulation stroke * Carotid dissection or tandem stenosis requiring treatment * Severe comorbidities or contraindications to imaging contrast
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time takes in achieving complete reperfusion after a single thrombectomy pass. | 24 hours or 48 hours after thrombectomy | To evaluate the superiority of the dual stentriever technique in achieving complete reperfusion after a single thrombectomy pass. |
Countries
Spain
Outcome results
None listed