Rectal Cancer Patients
Conditions
Keywords
circulating tumor cells
Brief summary
The prospective study will focus on patients undergoing multimodal treatment for rectal cancer. The main objective of the study will be to monitor changes in circulating tumor cells (CTCs) in the peripheral blood of patients during multimodal treatment. For each patient enrolled in the study, peripheral blood samples will be collected at specified time intervals to determine the presence and quantity of CTCs. The CTCs levels will be compared among rectal cancer patients with neoadjuvant chemoradiotherapy and without neoadjuvant chemotherapy.
Interventions
None listed
Sponsors
The Institute of Molecular and Translational Medicine, Czech Republic
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
rectal cancer -
Exclusion criteria
no other cancer \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Levels of circulating tumor cells in peripheral blood | The levels of circulating tumor cells will be measured in 5 time points: before neoadjuvant chemoradiotherapy, in 3. week of chemoradioterapy, before surgery, one week after surgery and one month after surgery. | The levels of circulating tumor cells will be measured in rectal cancer patients |
Countries
Czechia
Contacts
Primary ContactJosef Srovnal, Associate professor, MD, PhD
Outcome results
None listed