Association Between Peri-procedural Myocardial Injury and Quantitative Blood Flow Ratio

Association Between Angiography-based Quantitative Blood Flow Ratio and Peri-procedural Myocardial Injury：a Cohort Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07110298

Enrollment

200

Registered

2025-08-07

Start date

2019-01-01

Completion date

2023-05-31

Last updated

2025-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Arterial Disease (CAD)

Brief summary

to apply angiography-based quantitative blood flow ratio to quantify the severity of the stenosed coronary artery prior to percutaneous coronary intervention, and monitor per-procedural myocardial injury based on the troponin level.Finally, to find the relationship between quantitative blood flow ratio results and myocardial injury degree.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Inclusion criteria

* unstable angina patients

Exclusion criteria

* (1) multivessel diseases needed to be bypassed; (2) no track of high-sensitivity troponin I (hs-CTNI) level after PCI; (3) the elevated hs-CTNI level before PCI; (4) patients refusal to PCI; (5) side branch occlusion after PCI; (6) PCI failure with the main vessels occlusion; (7) eGRF (estimated glomerular filtration rate) less than 30ml/min/1.73m2; (8) no acquisition of QFR results because of the non-ideal angiographic quality.

Design outcomes

Primary

Measure	Time frame
cardiovascular adverse events	three months
Major cardiac adverse events	three months follow-up

Countries

China

Outcome results