Ovarian Stimulation Outcomes During a GnRH Antagonist Protocol for In-vitro Fertilization When Comparing Trigger Day Decision by Physicians Versus an Artificial Intelligence-based Algorithm.

Ovarian Stimulation Outcomes During a GnRH Antagonist Protocol for In-vitro Fertilization When Comparing Trigger Day Decision by Physicians Versus an Artificial Intelligence-based Algorithm - A Randomized Control Study.

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07110285

Enrollment

180

Registered

2025-08-07

Start date

2025-05-21

Completion date

2028-05-21

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IVF Outcomes

Keywords

Trigger day decision, In-vitro fertilization, Mature oocytes, Artifical intelligence-based algorithm

Brief summary

To compare the number of mature oocytes following a GnRH antagonist in-vitro fertilization stimulation cycle when comparing trigger day timing decision by physicians versus an artificial intelligence-based algorithm

Detailed description

Examination of all patients undergoing an ovarian stimulation cycle utilizing the GnRH antagonist protocol for oocyte cryopreservation or for fertilization via intracytoplasmic sperm injection (ICSI) (any treatment where oocytes are denuded and maturity may be assessed). The number of mature oocytes will be compared between cycles where trigger day timing was decided by the treating physician versus an artificial intelligence-based algorithm.

Interventions

OTHERArtificial intelligence-based algorithm

Trigger day timing decision by an artificial intelligence-based algorithm

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

* All patients undergoing an ovarian stimulation cycle utilizing the GnRH antagonist protocol for oocyte cryopreservation or for fertilization via intracytoplasmic sperm injection (ICSI) (any treatment where oocytes are denuded and maturity may be assessed).

Exclusion criteria

* Loss to follow-up, patient retracts consent to participate

Design outcomes

Primary

Measure	Time frame	Description
Mature oocyte yield	2 years	The number of mature oocytes collected during a single egg retrieval cycle

Secondary

Measure	Time frame	Description
Oocyte yield	2 years	Number of retrieved oocytes during an egg collection cycle

Countries

Israel

Contacts

Primary ContactMichal Youngster, MD

michalyo@gmail.com+972-50-643-0111

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026