Skip to content

European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis

European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis (ERGOSTE)

Status
Enrolling by invitation
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07108803
Acronym
ERGOSTE
Enrollment
2500
Registered
2025-08-07
Start date
2025-06-01
Completion date
2025-08-31
Last updated
2025-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infective Endocarditis (IE)

Keywords

Infective endocarditis, Cardiac surgery, Outcomes, Risk score, Prediction, In-hospital mortality, Pathogen agents, Statistics, Sepsis, Surgical techniques, Epidemiology

Brief summary

The European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis (ERGOSTE) is a nascent large surgical registry that would encompass most relevant aspects of IE in Europe in the contemporary era.

Detailed description

ERGOSTE, Purposes: * To create a European multicenter retrospective database including a large number of patients undergoing surgical treatment for infective endocarditis (IE). * To perform epidemiologic analyses of IE-patients and involved pathogens. * To find independent predictors of early post-operative death. * To test ALL the scoring systems specifically developed to predict early death after surgery for infective endocarditis. * To devise a specific risk score for early postoperative death. * To explore early and late outcomes of these very difficult patients in order to establish optimal indications, techniques and timing of surgery. * To carry out a number of sub-analyses concerning the demographic parameters and variable clinical presentation of patients, type and severity of cardiac structural involvement, adopted valve prostheses and surgical techniques, and different involved microbiologic agents. * To lay experiential foundations of a prospective database on the topic.

Interventions

None listed

Sponsors

Azienda Sanitaria Universitaria Giuliano Isontina (ASU GI)
Lead SponsorUNKNOWN

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients undergoing cardiac surgery due to infective endocarditis

Exclusion criteria

* Patients under 18 years

Design outcomes

Primary

MeasureTime frame
Early post-operative mortalityMortality at 1 year after surgery

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026