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Central Venous Oxygen Saturation Prognostic Impact in Post Arrest Patients

Central Venous Oxygen Saturation Impact on Prognosis of Post Arrest Patients

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07107776
Enrollment
30
Registered
2025-08-06
Start date
2025-08-01
Completion date
2027-08-01
Last updated
2025-08-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Arrest Patients

Keywords

post arrest patients, central venous oxygen saturation

Brief summary

The study aim will be to assess the prognostic impact and value of central venous oxygen saturation on post arrest patients.

Detailed description

Central venous oxygen saturation (ScvO₂) is a very important measurement which can be easily taken in a critical care environment by both medical and nursing staff. It provides an understanding of the patient's oxygen delivery, oxygen consumption and cardiac output. It has a key role within early goal-directed therapy and has been shown to decrease mortality when taken and analysed appropriately. (Central venous oxygen saturation: analysis, clinical use and effects on mortality,2013) Venous oxygen saturation (SvO2) measures the blood's oxygen content returning to the right side of the heart after perfusing the entire body. When the oxygen supply is insufficient to meet the metabolic demands of the tissues, an abnormal SvO2 ensues and reflects an inadequacy in systemic oxygenation. SvO2 is, therefore, dependent on oxygen delivery and oxygen extraction. Venous oximetry is used in specific clinical settings of hemodynamic instability, such as in critical illnesses, perioperative periods of major surgeries, heart failure, sepsis andd post arrest patients. The venous blood in the pulmonary artery represents oxygen extraction in the whole body and is called mixed venous oxygen saturation (SmvO2). It was measured using a pulmonary artery catheter (PAC). A second, less invasive method of measuring SvO2 is via a central venous catheter (CVC) positioned in the superior vena cava and is called the central venous oxygen saturation (ScvO2). Central venous oxygen saturation (ScvO(2)) is suggested to reflect the adequacy of oxygen delivery, and the main objective of the present study was to determine whether ScvO(2) is associated with outcome in haemodynamically stabilized post arrest patients predicting mortality and outcome based on central venous oxygen saturation

Interventions

None listed

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* adults above 16 years old, critically ill patients * both genders * post arrest patients

Exclusion criteria

* if patients does not experience cardiac arrest

Design outcomes

Primary

MeasureTime frameDescription
central venous oxygen saturation impact on prognosis of post arrest patientstime of follow up expected from time of successful ROSC until full improvement or recurrent arrest and death From date of cardiac arrest until date of first documented improvement or date of death due to any cause whichever came first assessed up in 2 moevaluating prognostic impact of oxygen saturation extracted from a central venous line blood sample on post arrest patients sample from (internal jagular vein) more or less than 50% oxygen saturation on prognosis of post arrest patients and recurrent arrests and overall improvement and time of expected and full recovery

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026