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Autism Traits in Adolescents With Social Anxiety Disorder: Associations With Parental Broader Autism Phenotype

Identification of Autism Traits in Adolescents With Social Anxiety Disorder and Evaluation of Their Association With the Broader Autism Phenotype in Their Parents

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07106840
Enrollment
109
Registered
2025-08-06
Start date
2024-01-11
Completion date
2025-03-01
Last updated
2025-08-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autistic Disorder, Social Anxiety Disorder (SAD)

Keywords

Phobia, Social, Anxiety, Autistic Disorder, Parents, Social Interaction

Brief summary

This observational study aims to examine autism-related traits in adolescents diagnosed with social anxiety disorder (SAD) and to evaluate their associations with broader autism phenotype (BAP) features in their parents. A total of 109 adolescents aged 11-17 and their parents were included. Standardized scales were used to assess social anxiety severity and autism traits in adolescents, and BAP characteristics in parents.

Detailed description

Autism spectrum traits and social anxiety share clinical and cognitive features, particularly in the domains of social communication and interaction. These overlaps suggest that autistic traits may be present in adolescents diagnosed with social anxiety disorder (SAD), even in the absence of a formal autism diagnosis. Furthermore, the concept of the broader autism phenotype (BAP) suggests that subclinical autism-related features may be observed in parents of individuals with autism traits. This study includes 109 adolescents (aged 11-17) diagnosed with SAD and their parents. The adolescents completed a standardized scale assessing social anxiety severity, while parents completed the Social Responsiveness Scale (SRS) for their children and the Autism Spectrum Quotient (AQ) to assess BAP characteristics in themselves. The study aimed to explore the associations between adolescents' autism-related traits and their social anxiety severity, and to evaluate how parental BAP scores (particularly fathers') may be associated with these traits. Note: This study involved prospective recruitment and data collection; however, registration was completed retrospectively after the study was completed.

Interventions

OTHERNo intervention (observational study)

This is an observational study with no intervention applied.

Sponsors

Ankara City Hospital Bilkent
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
11 Years to 17 Years
Healthy volunteers
No

Inclusion criteria

Adolescents aged 11-17 years diagnosed with Social Anxiety Disorder (SAB). Availability of at least one biological parent willing to participate. Ability to provide informed consent/assent.

Exclusion criteria

Presence of intellectual disability or severe neurological disorder. Comorbid psychiatric diagnoses that could interfere with assessment (e.g., psychosis). Non-fluency in the language of assessment.

Design outcomes

Primary

MeasureTime frameDescription
Social Anxiety SeverityAt baselineSeverity of social anxiety symptoms measured by the Social Anxiety Disorder Severity Scale - Child Form.

Secondary

MeasureTime frameDescription
Autism Traits in AdolescentsAt baselineAutism spectrum traits in adolescents assessed by the Social Responsiveness Scale, completed by parents.

Other

MeasureTime frameDescription
Parental Broader Autism PhenotypeAt baselineParental broader autism phenotype evaluated using the Autism Spectrum Questionnaire.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026