Aging
Conditions
Keywords
aging, biological age, immunosenescence, beta glucan
Brief summary
The primary purpose of this study is to evaluate the effects of BWH Labs - Beta Glucan 500 on biomarkers of biological and immune age among healthy adults. A single-arm, open-label prospective study will be conducted evaluating the impact of 12 weeks of supplementation with two capsules daily of Beta Glucan 500 on a variety of validated markers of biological and immune age on the comprehensive TruAge panel (TruDiagnostics, Lexington, KY).
Interventions
DIETARY_SUPPLEMENTBeta Glucan
12 weeks of supplementation with two capsules daily of BWH Labs Beta Glucan 500
Sponsors
OvationLab
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Adult females or males age ≥ 40 years 2. Ability to read and speak English 3. Previous completion of a TruDiagnostic TruAge test within the past three months to enable comparison of previous biomarkers to the same biomarkers after intervention 4. DunedinPACE estimate of aging \>0.9
Exclusion criteria
1. Current diagnosis and treatment for an autoimmune condition 2. Current use of beta-glucan or mushroom dietary supplement 3. Known allergies to beta glucan, yeast, or mushrooms 4. Currently pregnant or lactating women or women planning to become pregnant in the next 12 weeks 5. Current diagnosis of a chronic health condition (e.g., cancer, heart failure, history of pancreatitis, type I or II diabetics on insulin) deemed clinically contraindicated for the study protocol 6. Participants unable to provide consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Epigenetic Testing | Change from baseline to 12 weeks |
Countries
United States
Outcome results
None listed