Colorectal Cancer, Surgical Site Infections
Conditions
Brief summary
Surgical site infection (SSI) is a common complication following colorectal cancer (CRC) surgery and represents a significant cause of slower postoperative recovery and prolonged hospital stay. Therefore, this study aims to determine which risk factors contribute most to SSI development, and to assess the effectiveness of SENIC and NNIS scores in evaluating SSI risk after CRC surgery. This retrospective observational cohort study is conducted at the Oncology Institute of Vojvodina. Sixty-two patients are included, undergoing elective CRC surgery between 03.06.2024. and 31.10.2024. Data are collected from the information system and medical records, including demographic characteristics, presence of SSI, comorbidities, data regarding neoadjuvant oncological therapy, preoperative laboratory findings, type and duration of surgical intervention, perioperative complications, and SENIC and NNIS scores are calculated. The study is supported by a Collegium Talentum scholarship from the Ministry of Human Capacities (Hungarian Government), for the 2024/2025 academic year (recipient Nora Mihalek, MD). Contact: Nora Mihalek, MD Oncology Institute of Vojvodina, Department for Anesthesiology with Reanimatology, Sremska Kamenica, Serbia; University of Novi Sad, Faculty of Medicine, Novi Sad, Serbia
Interventions
Data are collected from the information system and medical records, including demographic characteristics, presence of surgical site infection, comorbidities, data regarding neoadjuvant oncological therapy, preoperative laboratory findings, type and duration of surgical intervention, perioperative complications, and SENIC and NNIS scores are calculated.
Sponsors
Oncology Institute of Vojvodina
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients (˃ 18 years of age) * ASA III clinical status * Patients undergoing radical surgical treatment of colorectal cancer
Exclusion criteria
\- Patients undergoing palliative surgical treatment of colorectal cancer
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of surgical site infection | During hospital stay (assessed up to 15 days) | Data collected from medical records and information system |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of particular risk factors for the development of surgical site infection (diabetes mellitus, anaemia, neoadjuvant chemotherapy, neoadjuvant radiotherapy) | Baseline | — |
| Incidence of particular risk factors for the development of surgical site infection (red blood cell transfusion, length of intervention > 3 hours, contaminated wound, ClassIntra classification, stoma formation) | Perioperative/Periprocedural | — |
| Study on the Efficacy of Nosocomial Infection Control (SENIC) score | Baseline | Maximal value: 4; Minimal value: 0 (higher score indicates worse outcome) |
| National Nosocomial Infection Surveillance (NNIS) score | Baseline | Maximal value: 3; Minimal value: 0 (higher score indicates worse outcome) |
Countries
Serbia
Outcome results
None listed