Comparison of Frequency of Wound Infection Between Open and Laparoscopic Cholecystectomy

Status

Recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07103707

Enrollment

122

Registered

2025-08-05

Start date

2025-08-31

Completion date

2026-08-31

Last updated

2025-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wound Infection, Surgical

Brief summary

The goal of this clinical trial is to compare the frequency of wound infection between open and laparoscopic cholecystectomy in adult patient aged 18- 65 years with symptomatic cholelithiasis admitted through OPD the main question it aims to answer are * Does there is difference in the frequency of wound infection in patients with open cholecystectomy as compared to laparoscopic cholecystectomy Researcher will compare the frequency of wound infection in participant undergoing open and laparoscopic cholecystectomy to see there is difference in frequency of wound infection between open and laparoscopic cholecystectomy Participants will be asked * To Visit OPD after 1 week for follow up * Keep record of symptoms like erythema, pain, cloudy drainage from the incision site

Interventions

PROCEDUREopen cholecystectomy

standard open cholecystectomy performed under general anesthesia

PROCEDURELaparoscopic cholecystectomy

Standard laparoscopic cholecystectomy using minimally invasive technique

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

OTHER

Masking

NONE

Intervention model description

randomization will performed by blocked randomization (61 in each group) 61 patient will be in open cholecystectomy group( A )while 61 patient will be in laparoscopic cholecystectomy group (B)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Both genders * Patients aged 18 to 65 years * Symptomatic cholelithiasis as per operational definition * Undergoing cholecystectomy (open/laparoscopic) * ASA score I/II (Annexure-II)

Exclusion criteria

* ● H/o diabetes mellitus * H/o immunocompromised state (e.g. HIV, steroid use) * H/o acute cholecystitis * H/o empyema gallbladder * H/o gallbladder perforation ● H/o choledocholithiasis * H/o portal hypertension * H/o abnormal blood clotting profiles (PTT \>15 seconds, APTT \>20 seconds) * H/o pregnancy on HCG

Design outcomes

Primary

Measure	Time frame	Description
comparison of frequency of wound infection between open and laparoscopic cholecystectomy	1 year	to compare the frequency of wound infection in patients undergoing open and laparoscopic

Countries

Pakistan

Contacts

Primary ContactMoeez u din khan, PGR GS

moeezk442@gmail.com+923489548857

Backup ContactIJAZ UL HAQUE, PGR NS

drijazulhaque712237@gmail.com+923499223911

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026