Muscle Fatigue
Conditions
Brief summary
Study Subjects: This study will recruit healthy males aged 18 to 35 who regularly exercise for at least 2.5 hours per week. Expected Number of Participants: 20. Methods and Procedures: This trial will be randomized into two groups, Groups A and B, who will undergo two isokinetic concentric exercise sessions (fatiguing exercise) separated by 15 days. Group A will first receive a fatigue prevention strategy (high-energy laser) followed by a placebo-controlled no-fatigue strategy 15 days later. Group B will first receive a placebo-controlled no-fatigue strategy followed by a fatigue prevention strategy (high-energy laser) 15 days later. The fatigue prevention strategy involves irradiating the quadriceps femoris with a 900-joule high-intensity laser therapy (3-watt output power for 5 minutes) before the isokinetic concentric exercise. The no-fatigue strategy (sham-controlled) involves irradiating the quadriceps femoris with a 0-joule high-energy laser (0-watt output power for 5 minutes) before the isokinetic concentric exercise. Muscle displacement, muscle excursion, as well as muscle electrophysiological changes, force output, and microcirculation parameters were measured before and after exercise to verify the feasibility of muscle displacement and migration for muscle fatigue assessment, and to further establish their impact and application value in muscle fatigue prevention strategies (high-intensity laser therapy).
Interventions
DEVICEhigh intensity laser therapy
The high-intensity laser used in this study is approved by the Ministry of Health and Welfare, Taiwan (No. 032670). It operates at a wavelength of 940 nm. For the active treatment (HILT), the laser delivers 900 joules to the quadriceps at a power output of 3 W for 5 minutes and is applied along the length of the quadriceps muscle
DEVICESham laser therapy
In the sham condition (SHAM), the output is set to 0 W for 5 minutes, resulting in no energy delivery.
Sponsors
National Taiwan University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
MALE
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* healthy male aged between 18 and 35 years who engage in regular physical activity for at least 2.5 hours per week
Exclusion criteria
* history of musculoskeletal injuries or lower limb muscle strains involving the dominant lower limb within the past six months * history of surgical interventions on the dominant lower limb
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle displacement | pre-fatigue (baseline), immediately post-fatigue, 5, 10, 20 minutes post-fatigue |
Countries
Taiwan
Outcome results
None listed