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The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic Surgery

Does Duration Matter? A Study on Single-Lung Ventilation Time and Pulmonary Complications in Thoracic Procedures

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07100860
Enrollment
134
Registered
2025-08-03
Start date
2025-01-01
Completion date
2026-01-01
Last updated
2025-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ards, One Lung Ventilation, Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications

Keywords

postoperative pulmonary complications, one lung ventilation

Brief summary

This observational study investigates the relationship between the duration of single-lung ventilation (SLV) and the incidence of postoperative pulmonary complications (PPCs) such as pneumonia, pneumothorax, hemothorax, acute lung injury, and acute respiratory distress syndrome (ARDS) in adult patients undergoing thoracic surgery. A total of 134 patients aged 18-85 years, scheduled for thoracic surgery requiring SLV, will be monitored. Data including SLV duration, perioperative parameters, and postoperative pulmonary outcomes will be analyzed.

Interventions

PROCEDUREOne-Lung ventilation

In this observational study, the naturally occurring duration of intraoperative single-lung ventilation (SLV) during thoracic surgery will be recorded. No intervention is applied or modified for research purposes. The exposure of interest is the total duration (in minutes) of SLV, which will be timed from initiation to termination during surgery. This variable will be analyzed in relation to postoperative pulmonary complications.

Sponsors

Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

Age ≥18 years Undergoing thoracic surgery OLV planned during the procedure

Exclusion criteria

Pediatric patients Patients not requiring OLV Previous thoracic surgery

Design outcomes

Primary

MeasureTime frameDescription
Postopertive Pulmonary Complicationspostoperative 7 daysPostoperative pulmonary complications (PPCs) are defined as respiratory events occurring within the first seven days following thoracic surgery, which negatively impact patient outcomes. In this study, PPCs include pneumonia, pneumothorax, hemothorax, acute lung injury, acute respiratory distress syndrome (ARDS), prolonged oxygen requirement, unplanned reintubation, and the need for non-invasive ventilation. These complications will be identified through clinical assessment, arterial blood gas analysis, and postoperative imaging such as chest X-rays. Each case will be evaluated using predefined diagnostic criteria to ensure consistency. The incidence of PPCs will be analyzed in relation to the duration of intraoperative single-lung ventilation.

Countries

Turkey (Türkiye)

Contacts

Primary ContactHazal EG AYTUĞ
drekinguran@gmail.com05078448449

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026