Spinal Metastasis as the First Presentation of Lung Malignancy: Clinical Characteristics and Postoperative Survival

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07100444

Enrollment

139

Registered

2025-08-03

Start date

2018-01-01

Completion date

2025-04-30

Last updated

2025-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Metastasis, Lung Cancers

Keywords

lung cancers, bone metastasis, spinal metastasis, postoperative survival outcomes

Brief summary

Detailed description

The aim of this study is to compare the clinical features and postoperative survival outcomes between patients with spinal metastasis as the initial manifestation of malignancy and those with spinal metastasis occurring after an established diagnosis of malignancy. By analyzing and contrasting these two groups, we seek to identify any distinctive characteristics, prognostic factors, and potential implications for early detection and treatment strategies in patients with malignant spinal metastases.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

1. Age ≥ 18 years. 2. Pathologically or radiologically confirmed diagnosis of lung cancer with spinal metastasis. 3. Patients with spinal metastasis who underwent surgical intervention. 4. Adequate medical records and follow-up data available.

Exclusion criteria

1. Patients with spinal metastasis originating from non-lung primary tumors. 2. Patients who did not receive surgical treatment for spinal metastasis. 3. Incomplete clinical data or lost to follow-up.

Design outcomes

Primary

Measure	Time frame	Description
Postoperative Overall Survival	From the date of surgery until death or last follow-up, up to 5 years	Postoperative overall survival is defined as the time from the date of surgery for spinal metastasis to the date of death from any cause. Patients who are still alive at the last follow-up will be censored at that date. Survival status will be ascertained by clinical follow-up and/or review of medical records.

Countries

China

Outcome results