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'Bubble Time' in Pulmonary Embolism

Diagnostic Value of Right Ventricular 'Bubble Time' in Pulmonary Embolism

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07098546
Enrollment
250
Registered
2025-08-01
Start date
2025-07-03
Completion date
2025-11-30
Last updated
2026-08-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tanısal değerlilik

Keywords

pulmonary embolism, bubble time, pocus

Brief summary

The study will be multi-centre and prospectively planned. All patients who undergo contrast-enhanced computed tomography in the emergency department with a preliminary diagnosis of pulmonary embolism and who do not meet the exclusion criteria will be included in the study. Informed consent will be obtained from all patients prior to the study. Patients included in the study will undergo bedside ultrasound to assess bubble time, right ventricle-left ventricle ratio, presence of a septal defect, and tricuspid insufficiency, and the diagnostic value of these findings will be evaluated. The bedside ultrasound will be part of the emergency department critical care examination, will not incur any costs for the institution, and will be performed and evaluated by an emergency medicine specialist and assistant.

Detailed description

The study will be multi-centre and prospectively planned. All patients who undergo contrast-enhanced computed tomography in the emergency department with a preliminary diagnosis of pulmonary embolism and who do not meet the exclusion criteria will be included in the study. Informed consent will be obtained from all patients prior to the study. Patients included in the study will undergo bedside ultrasound to assess bubble time, right ventricle-left ventricle ratio, presence of a septal defect, and tricuspid insufficiency, and the diagnostic value of these findings will be evaluated. The bedside ultrasound will be part of the emergency department critical care examination, will not incur any costs for the institution, and will be performed and evaluated by an emergency medicine specialist and assistant.

Interventions

None listed

Sponsors

Recep Tayyip Erdogan University Training and Research Hospital
Lead SponsorOTHER
Marmara University Pendik Training and Research Hospital
CollaboratorOTHER
Gazi University
CollaboratorOTHER
Akdeniz University Hospital
CollaboratorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

\- All patients presenting to the emergency department with any symptoms, undergoing pulmonary CT angiography due to suspected pulmonary embolism or evaluated as having a strong likelihood of embolism when CT cannot be performed will be included in the study.

Exclusion criteria

* Patients under the age of 18 * Patients with a severe history of tricuspid insufficiency * Patients with a severe of pulmonary hypertension * Patients with a severe of right heart failure * Patients without an echocardiographic report approved by cardiology within 48 hours after emergency admission * Patients in whom ultrasonographic measurements cannot be performed * Patients who refuse diagnosis and treatment voluntarily

Design outcomes

Primary

MeasureTime frameDescription
Bubble timethrough study completion, an average of six monthsThe diagnostic value of bubble time
bubble time in pulmonary embolismthrough study completion, an average of six monthsThe diagnostic value of bubble time in pulmonary embolism

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 12, 2026