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Impact of Previous Open Renal Surgery on Percutaneous Nephrolithotomy Complications

The Impact of Previous Open Renal Surgery on Percutaneous Nephrolithotomy Complications

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07097883
Enrollment
200
Registered
2025-07-31
Start date
2017-01-01
Completion date
2020-08-01
Last updated
2025-07-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications, Open Renal Surgery, Percutaneous Nephrolithotomy

Brief summary

This study compared percutaneous nephrolithotomy (PCNL) complications in cases with or without previous renal surgery.

Detailed description

Percutaneous nephrolithotomy (PCNL) is a cornerstone in managing large renal calculi. However, in patients with a history of previous open renal surgery (POS), retroperitoneal scarring, altered anatomy, and vascular complications may influence PCNL outcomes. The literature remains inconsistent regarding whether POS negatively impacts PCNL success or increases complications. Therefore, this study aims to clarify the comparative safety and efficacy of PCNL in patients with and without prior open renal surgery.

Interventions

PROCEDUREPercutaneous Nephrolithotomy

Patients underwent percutaneous nephrolithotomy (PCNL) for renal calculi \>2 cm.

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adult patients (≥18 years). * Both sexes. * Undergoing percutaneous nephrolithotomy (PCNL) for renal calculi \>2 cm.

Exclusion criteria

* Active urinary tract infection. * Elevated serum creatinine \>2.0 mg/dL. * Pregnancy. * Uncontrolled coagulopathy. * Significant cardiopulmonary comorbidities.

Design outcomes

Primary

MeasureTime frameDescription
Hospital stay durationTill the discharge from hospital (Up to two weeks)Lenght of hospital stay was recorded from the admission till the discharge from hospital.

Secondary

MeasureTime frameDescription
Serum creatinine levelPreoperativelySerum creatinine level was recorded.
Incidence of patients who need for auxiliary procedure24 hours postoperativelyIncidence of patients who need for auxiliary procedure were recorded.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026