Acute Decompensated Heart Failure
Conditions
Brief summary
Heart failure is a major global health issue requiring effective interventions to enhance patients' physical function and quality of life. Cardiac rehabilitation, particularly when started early during hospitalization for acute decompensated heart failure, has been shown to improve cardiovascular function, reduce hospital readmissions, and boost recovery. In-hospital exercise training enhances physical capacity, strengthens heart function, and alleviates physical limitations. On the other hand, lymphatic dysfunction in heart failure may also contribute to fluid retention, worsening the symptoms including lower extremity edema. Manual lymphatic drainage is considered a safe method to reduce edema and support fluid balance. This study aims to evaluate effects of in-hospital cardiac rehabilitation and manual lymphatic drainage on fluid overload symptoms and functional capacity in patients with acute decompensated heart failure.
Interventions
OTHERManual Lymphatic Drainage
Specific manual lymph drainage techniques including stationary circles, rotary circles, pumping, and scooping will be applied to both lower extremities using gentle, rhythmic skin movements in accordance with the direction of the lymphatic flow.
OTHERCardiac Rehabilitation
An individualized program consists of progressive, low-intensity exercises including respiratory exercises, range of motion exercises for major joints, postural exercises, flexibility exercises, and gradual mobilization exercises such as sitting and walking will be applied.
Sponsors
Istanbul University - Cerrahpasa
Yeditepe University
Saglik Bilimleri Universitesi
Izmir Bakircay University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients hospitalized with a diagnosis of acute decompensated heart failure * Being clinically stable
Exclusion criteria
* Having diagnosed pulmonary, neurological, renal, liver, gastrointestinal, orthopedic or oncological pathologies * Having cardiomyopathy or congestive pericarditis * Recent heart surgery in the past 6 months * New or suspected thromboembolic event * Presence of open wounds, ulcerations or major dermatological diseases in the lower extremities
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lower extremity edema | At baseline and at hospital discharge, up to 14 days after admission | Lower extremity edema will be evaluated by circumference measurement |
| Functional capacity | At baseline and at hospital discharge, up to 14 days after admission | Functional capacity will be measured using 6-min Walk Test. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Health-related quality of life | At baseline and at hospital discharge, up to 14 days after admission | Health-related quality of life will be evaluted using Short-Form 12 Questionnaire. It is scored between 0-100 and higher scores indicate better quality of life. |
Countries
Turkey (Türkiye)
Outcome results
None listed