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Eltrombopag Induced Liver Dysfunction During Treatment of Immunethrombocytopenic Purpura

Eltrombopag Induced Liver Dysfunction During Treatment of Immunethrombocytopenic Purpura

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07093606
Enrollment
100
Registered
2025-07-30
Start date
2025-07-14
Completion date
2026-01-20
Last updated
2025-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ITP - Immune Thrombocytopenia

Brief summary

this study amis to assess the incidence and severity of liver dysfunction in ITP patients receiving eltrombopag.

Interventions

DRUGEltrombopag

ITP patients will receive Eltrombopag and evulate occurance of liver disordres .

Sponsors

Sohag University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

Adult patients (≥18 years) diagnosed with primary ITP. Receiving eltrombopag as part of their treatment. Baseline liver function tests (LFTs) within normal limits. Patients with diabetes Patients without diabetes Patients with fatty liver Patients without fatty liver

Exclusion criteria

Pre-existing liver disease (e.g., hepatitis, cirrhosis, NAFLD). Concurrent use of hepatotoxic drugs. Patients lost to follow-up.

Design outcomes

Primary

MeasureTime frameDescription
•To assess the incidence and severity of liver dysfunction in ITP patients receiving eltrombopag.3-6 months after receiving eltombopagthe incidence and severity of liver dysfunction in ITP patients

Countries

Egypt

Contacts

Primary ContactPeter A Alfy, Resident
peter.adel.dola@gmail.com01274069691
Backup ContactUsama M Abdelaal, Professor
01065962094

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026