Opiophobia in Adults With Advanced Cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07093567

Enrollment

Registered

2025-07-30

Start date

2025-08-01

Completion date

2031-01-01

Last updated

2026-02-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer

Brief summary

To explore the barriers and fears related to use of opioids among a population of adult outpatients with advanced cancer who continue to experience pain after receiving a prescription for opioid analgesia and hypothesized associations among opiophobia, anxiety, depression, pain intensity, pain interference, and opioid medication adherence.

Detailed description

Primary Objective: To explore the barriers and fears related to use of opioids among a population of adult outpatients with advanced cancer who continue to experience pain after receiving a prescription for opioid analgesia. Secondary Objective: To examine associations among opiophobia, anxiety, depression, pain intensity, pain interference, and opioid medication adherence among adults with advanced cancer who report undermanaged pain during the first week after receiving a prescription for an opioid analgesic.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Adult patients with advanced cancer (defined as cancer that is unlikely to be cured and is locally advanced or distantly metastasized 2. Pain is the documented reason for the Supportive Care consultation 3. Have a prescription for an opioid analgesic 4. Able to read, speak, and consent in English.

Exclusion criteria

1. Age less than 18 years 2. Do not have a prescription for an opioid analgesic 3. Individuals for whom there is documentation of inability to provide consent in the medical record 4. Women who are pregnant 5. Patients with a substance use disorder (including alcohol use disorder and excluding tobacco use disorder) documented in the electronic health record under History of Present Illness or in the Medical History.

Design outcomes

Primary

Measure	Time frame
Barriers Questionnaire (BQ-13)	Through study completion; an average of 1 year

Countries

United States

Contacts

PRINCIPAL_INVESTIGATOREileen Hacker, PHD, RN

M.D. Anderson Cancer Center

Outcome results