Complex Regional Pain Syndrome (CRPS)
Conditions
Brief summary
Complex Regional Pain Syndrome (CRPS) is a condition triggered by trauma such as surgery or a fracture. It is characterised by pain and limited mobility that are disproportionate to the severity of the trauma and the clinical course. Magnesium is recognised for its anti-inflammatory and antioxidant properties. The magnesium depletion score (MDS) is a more reliable and comprehensive scoring tool than measuring serum and urine magnesium levels. This score takes into account the patient's use of diuretics and proton pump inhibitors, their alcohol consumption, and their glomerular filtration rate. Impaired magnesium distribution may be a risk factor for CRPS development due to increased nociceptor activity. This study aimed to investigate whether an increased MDS score is a risk factor for CRPS development in individuals with traumatic limb injury.
Interventions
OTHERscoring
magnesium depletion score calculation
Sponsors
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Study design
Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Male and female patients aged 18-99 years with traumatic extremity injuries
Exclusion criteria
* History of previous stroke, spinal cord injury * Presence of radiculopathy, radicular pain in the affected extremity * Previous surgery for cervical discopathy/lumbar discopathy * Presence of oncological, haematological diseases * History of previous peripheral nerve injury or previous surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| CRPS development | baseline | crps development will be assessed according to Budapest criteria |
Countries
Turkey (Türkiye)
Outcome results
None listed