Care Pathways and Disparities in Care for Older Patients With Cancer: Typology, Determinants and Effect on Prognosis ( PASSAGE )

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07092800

Acronym

PASSAGE

Enrollment

75000

Registered

2025-07-30

Start date

2024-09-07

Completion date

2028-08-31

Last updated

2025-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aged, Cancer, Causality, Geriatric Assessment, Health Services Research, Tumor

Keywords

Frailty, care pathways, cancer, ageing

Brief summary

More than half of new cases of cancer in Europe in 2022 occurred in people aged over 70. In addition to cancer, the majority of older people have one or more illnesses that may interact with the treatment decision, cancer progression, tolerance and efficacy of treatments, quality of life, care pathway and survival. Furthermore, cancer treatments are most often evaluated in middle-aged subjects without severe disease, so the real-life management of older patients is often empirical. The general objective of the PASSAGE project is to assess the hospital care pathways of older patients with cancer treated at AP-HP by evaluating key elements of these pathways from both geriatric and therapeutic perspectives. Characterizing these care trajectories will help identify the most vulnerable patient profiles and potential disparities in access to care, with the goal of optimizing the management of elderly patients with cancer. The aims of this research are 1) to provide a better description of trends in the management of older cancer patients in routine clinical practice, and 2) to assess the impact of frailty, multimorbidity and the management of these patients on the prognosis of the disease.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

70 Years to 130 Years

Healthy volunteers

Inclusion criteria

* Patients aged 70 or over, * Having at least one International Classification of Disease, 10th revision (ICD-10) for solid cancer recorded as principal diagnostic or related, * During treatment in an AP-HP hospital, * Between 01/08/2017 and 31/07/2023.

Exclusion criteria

* opposition to the reuse of healthcare data

Design outcomes

Primary

Measure	Time frame	Description
type of care pathway	from cancer diagnosis during a year of follow-up	The primary endpoint is the type of care pathway as identified by longitudinal clustering analysis of Electronic Health Record (EHR) data in the year following diagnosis (medical diagnoses, procedures, admissions, treatment received),.

Countries

France

Outcome results