Neurobehavioral Mechanisms of Moral Reasoning: an EEG Study in Patients With Borderline Personality Disorder

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07091409

Enrollment

Registered

2025-07-29

Start date

2024-10-01

Completion date

2025-07-20

Last updated

2025-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Borderline Personality Disorder (BPD)

Brief summary

We will investigate social cognition in patients with Borderline personality disorder (BPD) combined with electroencephalographic (EEG) measures.

Detailed description

We will investigate whether patients with Borderline personality disorder (BPD) show a negativity bias in evaluating social situations. We will also asses emotional arousal, theory of mind (ToM) abilities, and inhibitory control in patients with BPD. In addition to behavioral outcome variables, electroencephalographic (EEG) measures will be recorded. Healthy controls server as a control group.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

BPD diagnosis BMI between 17.5 and 30 acute major depressive episode, psychotic symptoms, substance addiction or acute suicidal behavior

Exclusion criteria

neurological, metabolic, endocrine, autoimmune and CNS diseases, any other severe somatic diseases, and pregnancy or breastfeeding during the last 12 months

Design outcomes

Primary

Measure	Time frame	Description
Number of accidental harm scenarios misclassified as intentional	20 Minutes	Accuracy

Countries

Germany

Outcome results