Evaluation of Dentoalveolar Changes of Clear Aligners Versus Fixed Orthodontic Appliances on Skeletal Class I Non-extraction Patients With Dental Crowding

Evaluation of Dentoalveolar Changes of Clear Aligners Versus Fixed Orthodontic Appliances on Skeletal Class I Non-extraction Patients With Dental Crowding: Randomized Controlled Clinical Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT07090746

Enrollment

Registered

2025-07-29

Start date

2023-12-30

Completion date

2026-01-01

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skeletal Class I Non-extraction Patients With Dental Crowding

Keywords

clear aligners

Brief summary

To evaluate dentoalveolar changes of clear aligners versus fixed orthodontic appliances on skeletal class I non-extraction patients with dental crowding.

Interventions

DEVICEClear aligner

Clear aligner

DEVICEFixed orthodontic appliance

Fixed orthodontic appliance

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 22 Years

Healthy volunteers

Inclusion criteria

* Complete permanent dentition. * Angle Class I malocclusion cases with mild to moderate crowding (2-6 mm) that can be resolved by dental expansion and interproximal reduction (IPR). * Good oral hygiene.

Exclusion criteria

* Bad oral hygiene. * Previous orthodontic treatment. * Periodontal disease and previous periodontal surgery procedures. * Systemic diseases and/or craniofacial syndromes.

Design outcomes

Primary

Measure	Time frame	Description
Alveolar bone thickness	From date of randomization until the date of first documented acceptable teeth alignment, assessed up to 12 months.	Alveolar bone thickness will be assessed in vestibular and oral sides, parallel to the cervical reference line (CRL) at 3 different evels and expressed in millimeters.
Alveolar bone height	From date of randomization until the date of first documented acceptable teeth alignment, assessed up to 12 months.	Alveolar bone height loss will be measured perpendicularly to the CRL in both vestibular and oral sides. It will be represented as the difference between pretreatment and post treatment distance from alveolar crest to the CRL, expressed in millimeters.

Secondary

Measure	Time frame	Description
Comparison of transverse dental changes between the two groups.	From date of randomization until the date of first documented acceptable teeth alignment, assessed up to 12 months.	Assessment of inter-molar and inter-canine widths
Assessment of Apical root resorption	From date of randomization until the date of first documented acceptable teeth alignment, assessed up to 12 months.	comparison of root length changes after treatment

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026