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Acute Effects of Progressive Muscle Relaxation on Brain Waves

Acute Effects of Progressive Muscle Relaxation on Brain Waves, Heart Rate Variability, Muscle Tone, and Mental Stress

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07089537
Enrollment
32
Registered
2025-07-28
Start date
2025-02-24
Completion date
2025-12-31
Last updated
2025-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Progressive Muscle Relaxation

Brief summary

In modern environments, stress is present regardless of age or social role. Stress does not always have negative effects; in fact, it is a necessary response for survival, known as the stress response. This response includes increased heart rate, blood pressure, blood glucose levels, and decreased alpha brainwave activity. These physiological changes are primarily regulated by the sympathetic and parasympathetic branches of the autonomic nervous system, enabling us to cope with environmental threats. However, when the stress response system becomes overwhelmed or imbalanced-whether due to accumulated chronic stress or acute stress-it may result in adverse effects on both physical and mental health. Relaxation techniques are non-pharmacological methods that promote parasympathetic nervous system activity. The goal is to reduce excessive arousal, alleviate anxiety, slow down thought processes, and relieve stress, thereby achieving relaxation in a natural way. These methods help lower blood pressure, improve circulation, relax muscles, and enhance concentration. Previous studies have demonstrated a correlation between relaxation and attention, suggesting that relaxation can improve attentional efficiency. Moreover, it is well-documented that executive function tends to decline under stress. Relaxation techniques are commonly incorporated into psychological therapies, yet they are more accessible, easier to practice, and can be conveniently performed at home. Therefore, the aim of this study is to investigate whether PMR can produce immediate relaxation effects as measured by EEG (cortical excitability), heart rate variability, and muscle tone, and whether it can improve performance under psychological stress. The goal is to further explore the potential application of PMR in healthy populations facing acute stress conditions.

Interventions

OTHERprogressive muscle relaxaiton

Participants will undergo approximately 30 minutes of Progressive Muscle Relaxation (PMR). Prior to the session, a brief introduction to the basic concepts of PMR will be provided. Participants will be instructed to close their eyes and focus on the sensations in their muscles. Following verbal instructions, they will sequentially contract and relax 14 major muscle groups from top to bottom. For each muscle group, participants will be asked to contract the muscles as strongly as possible for 7 seconds, followed by a 45-second relaxation period. This process will be repeated twice for each muscle group.

OTHERRest

Rest in a semi-recumbent position with eyes closed for 30 minutes, without any additional intervention.

Sponsors

Kaohsiung Medical University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Healthy adults * Age: 18 years and above * Body Mass Index (BMI) between 18 and 24 * Able to remain in a semi-recumbent position for 2 hours

Exclusion criteria

* Individuals with communication impairments or difficulty understanding instructions * Color vision deficiency * Open wounds or injuries on the scalp * Currently taking medications that affect cardiovascular or autonomic nervous system regulation * Muscle strain or pain

Design outcomes

Primary

MeasureTime frameDescription
Electroencephalography20 min in totalAnalysis of changes in EEG band power excitability across the frontal, central, and occipital brain regions.

Secondary

MeasureTime frameDescription
Muscle tension15 minsChanges in muscle tension
heart rate variability20 mins in totalchanges in frequency domain heart rate variability
Self-Assessment Manikin1minWhether the subjective emotion is calm or excited

Countries

Taiwan

Contacts

Primary ContactMiaoju Hsu
mjhsu@kmu.edu.tw886+73121101
Backup ContactHsinyu Sun
bearcat97203@gmail.com886+989663315

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026