Gastrointestinal
Conditions
Brief summary
Recent studies from Asia have reported a wide variation in the incidence of deep vein thrombosis (DVT), ranging from 5% to 50% in patients undergoing major abdominal surgery. However, data specific to the Nepalese population remains unavailable. This study aims to evaluate current thromboprophylaxis practices and determine the incidence of DVT in Nepalese adults undergoing gastrointestinal and hepatobiliary surgery.
Interventions
major gastrointestinal or hepatobiliary surgery under general anesthesia
Sponsors
Study design
Eligibility
Inclusion criteria
* Adults aged \>18 years * Underwent major gastrointestinal or hepatobiliary surgery * Surgery performed under general anesthesia * Major surgery defined as any operative intervention in the abdominal or hepatobiliary region requiring general anesthesia
Exclusion criteria
* History of VTE within 3 months before surgery * Known hypercoagulable state or congenital thrombophilia * Diagnosis of atrial fibrillation * Undergoing systemic cancer chemotherapy or radiotherapy within the past 15 days * Pregnant or lactating women * Missing information in clinical records * Non-operated patients or those receiving conservative management * Patients undergoing liver transplantation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Use of Thromboprophylaxis and Incidence of DVT in Major GI and Hepatobiliary Surgeries | From date of surgery until hospital discharge or up to 30 days postoperatively, whichever occurs first | This outcome assesses the proportion of patients receiving appropriate thromboprophylaxis, as well as the incidence of deep vein thrombosis (DVT) among individuals undergoing major gastrointestinal and hepatobiliary surgeries. Data will be collected to evaluate adherence to prophylaxis guidelines and to determine the effectiveness of thromboprophylactic measures in preventing DVT in this surgical population. |
Countries
Nepal