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Practice of Deep Venous Thrombosis Prophylaxis and Its Incidence in Patients Undergoing Gastrointestinal and Hepatobiliary Surgery

Practice of Deep Venous Thrombosis Prophylaxis and Its Incidence in Patients Undergoing Gastrointestinal and Hepatobiliary Surgery: A Nepalese Single-center, Retrospective Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07088575
Enrollment
1530
Registered
2025-07-28
Start date
2024-05-23
Completion date
2024-07-24
Last updated
2025-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal

Brief summary

Recent studies from Asia have reported a wide variation in the incidence of deep vein thrombosis (DVT), ranging from 5% to 50% in patients undergoing major abdominal surgery. However, data specific to the Nepalese population remains unavailable. This study aims to evaluate current thromboprophylaxis practices and determine the incidence of DVT in Nepalese adults undergoing gastrointestinal and hepatobiliary surgery.

Interventions

PROCEDUREmajor gastrointestinal or hepatobiliary surgery under general anesthesia

major gastrointestinal or hepatobiliary surgery under general anesthesia

Sponsors

Maharajgunj Medical Campus
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adults aged \>18 years * Underwent major gastrointestinal or hepatobiliary surgery * Surgery performed under general anesthesia * Major surgery defined as any operative intervention in the abdominal or hepatobiliary region requiring general anesthesia

Exclusion criteria

* History of VTE within 3 months before surgery * Known hypercoagulable state or congenital thrombophilia * Diagnosis of atrial fibrillation * Undergoing systemic cancer chemotherapy or radiotherapy within the past 15 days * Pregnant or lactating women * Missing information in clinical records * Non-operated patients or those receiving conservative management * Patients undergoing liver transplantation

Design outcomes

Primary

MeasureTime frameDescription
Use of Thromboprophylaxis and Incidence of DVT in Major GI and Hepatobiliary SurgeriesFrom date of surgery until hospital discharge or up to 30 days postoperatively, whichever occurs firstThis outcome assesses the proportion of patients receiving appropriate thromboprophylaxis, as well as the incidence of deep vein thrombosis (DVT) among individuals undergoing major gastrointestinal and hepatobiliary surgeries. Data will be collected to evaluate adherence to prophylaxis guidelines and to determine the effectiveness of thromboprophylactic measures in preventing DVT in this surgical population.

Countries

Nepal

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026