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Joshi's Step With Buccal Mucosal Graft Urethroplasty in Nearly Obliterated Bulbar Urethral Stricture

Joshi's Step With Buccal Mucosal Graft Urethroplasty in Nearly Obliterated Bulbar Urethral Stricture: A Prospective Study

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07088198
Enrollment
50
Registered
2025-07-28
Start date
2024-05-01
Completion date
2025-11-01
Last updated
2025-07-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Buccal Mucosal Graft, Joshi's Step, Obliterated Bulbar Urethral Stricture, Urethroplasty

Brief summary

This study aims to evaluate the functional and surgical outcome of Joshi's step with buccal graft urethroplasty for the management of nearly obliterated bulbar urethral stricture.

Detailed description

Urethroplasty is a rapidly evolving art that continually improves and reinvents itself. After a century of silence, during which the anastomotic repair was the only solution for approaching the strictured urethra, the 1990s can be considered the Renaissance period for reconstructive urology. In 2022, Joshi and Kulkarni introduced a new step to the augmented urethroplasty, particularly in patients with extremely narrow strictures where a single augmentation was insufficient. They avoid any resection of the residual native urethral plate, marking the narrowest portion. Then, the edges of the mucosa are reapproximated with interrupted suturing in a proper non-resecting approach.

Interventions

PROCEDUREJoshi's step

Patients will undergo dorsal onlay buccal mucosal graft urethroplasty with Joshi's step

Sponsors

Tanta University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients with primary bulbar urethral stricture. * Patients with non-traumatic bulbar urethral stricture. * Patients with nearly obliterated bulbar urethral stricture, with the narrowest portion of the stricture is less than 1.5 cm in length.

Exclusion criteria

* Patients with traumatic bulbar urethral stricture. * Patients with redo bulbar urethral stricture. * Patients with obliterated bulbar urethral stricture. * Patients with nearly obliterated long bulbar urethral stricture.

Design outcomes

Primary

MeasureTime frameDescription
Success rate6 months postoperativelyIncidence of success rate will be recorded.

Secondary

MeasureTime frameDescription
Urine flow rate6 months postoperativelyUrine flow rate will be recorded.
The urethral lumen6 months postoperativelyThe urethral lumen by ascending urethrogram will be recorded.

Countries

Egypt

Contacts

Primary ContactMohamed I Elmaadawy, MD
Mohamed.elmaadawy@med.tanta.edu.eg00201060245430

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026