Skip to content

Optimizing Hamstring Rehabilitation With Amino Acids

Optimizing Hamstring Rehabilitation With Amino Acids: A Randomized Controlled Study for Seamless Return to Sports in Football Athletes

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07086209
Enrollment
25
Registered
2025-07-25
Start date
2025-09-19
Completion date
2025-10-20
Last updated
2025-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seamless Return to Sports

Keywords

Hamstring Rehabilitation, Return to play, Amino Acids, Football

Brief summary

Hamstring injuries are among the most prevalent and troublesome injuries in athletes, particularly those engaged in sports that require high-speed movements such as sprinting, kicking, and rapid changes in direction. The hamstring muscles, which include the biceps femoris, semitendinosus, and semimembranosus, are essential for powerful lower limb actions, and thus, any injury to these muscles can significantly impact an athlete's performance and recovery. These injuries often occur during eccentric muscle contractions, such as when the muscles lengthen rapidly under tension, as seen in running and sprinting. According to epidemiological studies, hamstring strains account for a substantial portion of sports-related injuries, with hamstring strains being the most commonly reported injury in disciplines such as football, soccer, rugby, and athletics. In professional football, for instance, hamstring injuries account for approximately 12% of all injuries and represent the most frequent muscle strain, underlining their significance in the context of athletic performance.

Interventions

DIETARY_SUPPLEMENTBranched-Chain Amino Acid Supplement

Oral BCAA blend (leucine, isoleucine, valine), 10 g/day divided into two doses, pre- and post-training, for 6 weeks.

6-week structured program including isometric, eccentric, plyometric, and sprint-specific exercises.

Sponsors

Universidad de Zaragoza
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
OTHER
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
No minimum to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* • Male football players aged 18 to 35 years. * Active players from eight clubs in the Iraqi Football League. * MRI-confirmed partial hamstring muscle injury. * No participation in other ongoing rehabilitation programs.

Exclusion criteria

* • History of hamstring injury in the past six months. * Any other musculoskeletal injuries affecting lower limbs. * Contraindications for MRI scanning (e.g., metal implants, pacemakers). * Any existing neurological or metabolic conditions affecting muscle recovery.

Design outcomes

Primary

MeasureTime frameDescription
Change in Hamstring Muscle StrengthBaseline, Mid-Rehabilitation (Week 3), Post-Rehabilitation (Week 6)Isometric knee flexion strength measured at 15° and 90° using the ForHealth Kit to assess change from baseline.

Secondary

MeasureTime frameDescription
MRI FindingsBaseline and Post-Rehabilitation (Week 6)MRI assessment of muscle healing, including reduction in edema and tear resolution.

Other

MeasureTime frameDescription
Adherence to RehabilitationThroughout 6-week intervention periodPercentage of rehabilitation sessions attended by each participant, tracked via attendance logs.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026