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Relationship Between Serum Markers and Motor Recovery and Ambulation in Post-stroke Patients

Relationship Between Serum Markers and Motor Recovery and Ambulation in Post-stroke Patients: a Retrospective Analysis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07086092
Enrollment
257
Registered
2025-07-25
Start date
2025-07-15
Completion date
2025-07-15
Last updated
2025-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biomarkers, Serum Magnesium, Serum Uric Acid, Serum Vitamin D, Stroke

Brief summary

This study aim to retrospectively investigate the effects of the magnesium, vitamin D, and uric acid serum markers on motor recovery and ambulation in post-stroke patients.

Detailed description

Stroke is the sudden loss of neurological function associated with a reduction or cessation of blood flow in the brain, resulting from the blockage or rupture of cerebral vessels. Stroke is the second leading cause of death and the third leading cause of disability worldwide. Regaining motor recovery and ambulation skills in patients is one of the main goals of rehabilitation. It is critical for patients to improve their quality of life and regain their independence. Serum biochemical markers can be used to predict post-stroke recovery. Serum magnesium, vitamin D, and uric acid are biochemical markers that may play a role in the recovery process of stroke patients. This study aim to retrospectively investigate the effects of the magnesium, vitamin D, and uric acid serum markers on motor recovery and ambulation in post-stroke patients.

Interventions

OTHERSerum magnesium, uric acid, and vitamin D levels and motor recovery and ambulation stages

Serum magnesium, uric acid, and vitamin D levels, as well as motor recovery and ambulation levels, measured during the patients' rehabilitation stay will be obtained from past medical records.

Sponsors

Abant Izzet Baysal University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
30 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* Patients who had a single stroke between 2019 and 2024 * Patients who were admitted to the rehabilitation ward and had their serum vitamin D, magnesium, and uric acid levels measured * Patients whose functional ambulation scale scores and Brunnstrom motor recovery stages were recorded

Exclusion criteria

* Patients with other neurological diseases * Patients with multiple strokes * Patients with gout, renal failure, or hyperparathyroidism

Design outcomes

Primary

MeasureTime frameDescription
Serum magnesium levelsBefore treatmentSerum magnesium levels measured before the patients' rehabilitation will be obtained from past medical records.
Serum uric acid levelsBefore treatmentSerum uric acid levels measured before the patients' rehabilitation will be obtained from past medical records.
Serum vitamin D levelsBefore treatmentSerum vitamin D levels measured before the patients' rehabilitation will be obtained from past medical records.
Brunnstrom Motor Recovery StageBefore treatmentBrunnstrom stages is a scale used to assess motor recovery after a stroke, which is expressed using values between 1 and 6. The higher the value on this scale, the higher would be the recovery. Brunnstrom Motor Recovery Stages measured before the patients' rehabilitation will be obtained from past medical records.
Functional Ambulation ClassificationBefore treatmentFunctional Ambulation Classification is a 6-point functional walking test that evaluates ambulation ability and determines the amount of human support required by patients while walking, regardless of whether they use a personal assistive device. A score of 0 indicates that the patient has a dysfunctional ambulation A score of 5 denotes independent ambulation on any surface. Functional Ambulation Classification Stages measured before the patients' rehabilitation will be obtained from past medical records.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026