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Association Between Isokinetic Lower Extremity Muscle Strength and Bone Mineral Density in Elderly Women With and Without Osteoporosis

Association Between Isokinetic Lower Extremity Muscle Strength and Bone Mineral Density in Elderly Women With and Without Osteoporosis: A Case-Control Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07084857
Enrollment
70
Registered
2025-07-25
Start date
2025-02-08
Completion date
2025-03-29
Last updated
2026-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis

Keywords

Osteoporosis, Bone Mineral Density, Isokinetic Strength;, Hip Muscles, Knee Muscles

Brief summary

bone density and muscle strength appear to be more related to each other. Examining the association between muscle strength and bone health is very important in recognizing risk factors for lower extremity muscle weakness.

Detailed description

Dual Energy X-ray Absorptiometry (DEXA) scan will be used to assess hip bone mineral density (BMD) at femoral head region. Isokinetic PT of hip flexors, extensors, abductors and adductors and knee flexors and extensors will be measured using Biodex System 3 Isokinetic Dynamometer. The measured outcomes will be evaluated at an angular velocity of 60°/sec in a concentric mode of muscle contraction for five successive repetitions. Isokinetic testing will be done at the Isokinetic Laboratory, Faculty of Physical therapy, Cairo University.

Interventions

OTHERcorrelational analysis between BMD and isokinetic lower extremity strength

correlational analysis between BMD and isokinetic lower extremity strength

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
50 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

1. The group of OP (n=33) has femoral BMD T-scores below -2.5 diagnosed by DEXA scan according to the WHO \[8\] classification of BMD in 2003, 2. The control group has normal BMD T-scores more than -1.

Exclusion criteria

1. There was any neurological, musculoskeletal, rheumatologic, respiratory or cardiovascular problem. 2. They were receiving medications that result in bone loss such as corticosteroids, 3. They had vertigo, dizziness, or any vestibular problem, 4. They had hyperthyroidism or hyperparathyroidism. 6- They actively participate in sports activities, 5. They underwent previous surgery (e.g; joint replacement) or history of fractures of the lower extremity.

Design outcomes

Primary

MeasureTime frameDescription
isokinetic strength of hip musclesone monthisokinetic hip muscle stregth will be measured using Biodex system 3 Isokinetic Dynamometer
Bone mineral densityone monthbone mineral density measured by dual energy x ray absorptiometry scan

Secondary

MeasureTime frameDescription
isokinetic strength of knee musclesone monthisokinetic hip muscle stregth will be measured using Biodex system 3 Isokinetic Dynamometer

Countries

Egypt

Contacts

PRINCIPAL_INVESTIGATORAzza M Abdelmohsen, professor

Cairo University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 9, 2026