Mechanical Ventilation, Weaning Failure, Weaning From Mechanical Ventilation
Conditions
Keywords
Parasternal thickening; failed weaning; extubation
Brief summary
optimal time to liberate from mechanical ventilation is highly prioritized since improper extubation time lead to serious consequences
Detailed description
Several parameters were proposed to assess proper weaning time including diaphragmatic ultrasound and extra-diaghragmatic muscles. previous research concluded an ability of parasternal intercostal (PIC) thickening to predict weaning outcomes. researchers of current study assumed that temporal changes in PIC thickening would provide greater ability to predict weaning outcomes
Interventions
DEVICEParasternal intercostal thickening
Temporal change in parasternal intercostal thickening fraction at initiation and 30 minutes of spontaneous breathing trial
Sponsors
Cairo University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
\- Mechanically ventilated for 24 hours or more ready for weaning
Exclusion criteria
* Refusal Tracheostomized Inability to obtain ultrasound views patients with neuromuscular disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy of change in PIC-TF in predicting successful weaning from mechanical ventilation | At baseline and 30 minutes after initiation of spontaneous breathing trial | percentage of change in PIC TF in predicting weaning outcome (PIC TF30-PIC TF0) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy of change in PIC-TF to predict reintubation | At baseline and 30 minutes after initiation of spontaneous breathing trial | percentage of change in PIC TF at start and end of spontaneous breathing trial (PIC TF30-PIC TF0) |
Countries
Egypt
Outcome results
None listed