AB-1005 Long-Term Follow-up Study

Long-Term Safety and Efficacy Follow-up of AB-1005 Gene Transfer Study Participants With Parkinson's Disease or Multiple System Atrophy

Status

Enrolling by invitation

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT07081841

Enrollment

132

Registered

2025-07-23

Start date

2025-09-04

Completion date

2038-03-30

Last updated

2025-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple System Atrophy, Parkinson Variant, Parkinson's Disease

Brief summary

This is an observational, long term, follow-up study for participants with Parkinson's disease (PD) or Multiple System Atrophy-Parkinsonian subtype (MSA-P) who participated in prior interventional studies with AB-1005. It is intended to better understand the long-term safety of AB-1005, how well tolerated it is and how long lasting the effects are.

Interventions

OTHERObservation

This is an observational study in which safety laboratories and non-invasive routine clinical assessments are conducted to gauge long term safety and efficacy.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* PD and MSA-P participants that are or were enrolled in an interventional AB-1005 study and provide informed consent

Exclusion criteria

* There are no

Design outcomes

Primary

Measure	Time frame	Description
Long term safety and tolerability	Up to 10 years post surgery	Measure of the occurrence of serious and non-serious adverse events

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026