Obsessive-Compulsive Disorder (OCD)
Conditions
Keywords
Obsessive-Compulsive Disorder, Cognitive-behavior therapy, icbt, Online treatment, e-health
Brief summary
The goal of the study is to assess the feasibility, acceptability, and potential effects of therapist-guided internet-delivered cognitive-behavior therapy (iCBT) for adult obsessive-compulsive disorder, using a recently developed digital platform.
Detailed description
Although cognitive-behavior therapy (CBT) is a well-established first-line treatment for many mental disorders, very few patients receive it due to the shortage of trained professionals, the costs of face-to-face therapy, and geographic barriers. Therapist-guided internet-delivered CBT (iCBT) is a potential solution to this problem but is not generally available in our context. The investigators plan to: 1. Develop a digital platform for the treatment of mental disorders using therapist-guided iCBT; 2. Assess the feasibility, acceptability, and potential effects of therapist-guided iCBT for adult obsessive-compulsive disorder (OCD) using the platform developed in Objective 1.
Interventions
BEHAVIORALicbt
12-Week Therapist-Based iCBT for OCD (Adapted Version of OCD Net: https://therapistguide.webcbt.se/index.html)
Sponsors
Hospital Clinic of Barcelona
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Single-Group Assignment
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Age between 18 and 75 * Internet access * Principal diagnosis of OCD, based on DSM-5 * Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) Total Severity Score \> 16 * Ability to communicate in Spanish * For participants taking psychotropic medication for OCD: at least eight weeks on stable medication and willingness to stay on the same medication/doses for the 12 weeks of the study
Exclusion criteria
* Estimated IQ \< 70, as per the Vocabulary subtest of the Wechsler Adults Intelligence Scale for Children (WISC) * Eight or more previous sessions of CBT for OCD with an experienced therapist during the last 12 months * Ongoing psychological treatment for OCD * Diagnosis of organic brain disorder, intellectual disability, autism spectrum disorder, psychosis, bipolar disorder, low-weight anorexia nervosa, or alcohol/substance dependence * Immediate risk to self or others (e.g., suicidality) * Inability to communicate in Spanish * Low motivation to participate (i.e., the patient does not believe the therapy will be helpful at all) * Insufficient time to work on the treatment (about 30 minutes per day)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Feasibility (recruitment and retention rates and therapist burden) | From enrollment to the end of treatment at 12 weeks | The investigators will assess feasibility by recording recruitment rates, retention rates, and therapist burden (time spent by the therapist sending emails, reviewing materials, etc.). |
Other
| Measure | Time frame | Description |
|---|---|---|
| Yale-Brown Obsessive-Compulsive Scale | Baseline and 12 weeks | The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) evaluates the severity of obsessive-compulsive disorder symptoms in adults. It is a clinician-rated, 10-item scale, with each item rated from 0 (no symptoms) to 4 (extreme symptoms), resulting in a total score ranging from 0 to 40. The scale also provides separate subtotals for the severity of obsessions and compulsions. |
| Clinical Global Impression (CGI)-Severity | Baseline and 12 weeks | The CGI rates the severity of the patient's illness at the time of assessment on a 7-point scale, from 1 = normal to 7 = among the most extremely ill patients. |
| Acceptability (Treatment Acceptability/Adherence Scale, TAAS) | Immediately after the intervention | The TAAS assesses satisfaction with treatment and adherence. |
| Negative Effects Questionnaire (NEQ) | Baseline, mid-intervention and 12-weeks | The NEQ assesses potential negative side effects of the intervention. |
| Obsessive-Compulsive Inventory Revised (OCI-R) | Baseline and after 12 weeks | The OCI-R assesses obsessive-compulsive symptoms experienced over the past month. It is an 18-item self-report questionnaire covering six symptom dimensions: washing, checking, ordering, obsessing, hoarding, and neutralizing. Each item is rated on a 5-point scale (0 = not at all, 4 = extremely), reflecting the distress caused by the symptom during the past month. |
| Beck Depression Inventory | Baseline and 12 weeks | The BDI assesses the severity of depressive symptoms in adolescents and adults. |
Contacts
Primary ContactMiquel A Fullana, PhD
Backup ContactMaria Sagué, MD
Outcome results
None listed