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the Effect of Adult Intubated Patient Clinical Pathway on Post-extubation Complications Prevention

the Effect of Adult Intubated Patient Clinical Pathway on Post-extubation Complications Prevention

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT07081399
Acronym
CP
Enrollment
80
Registered
2025-07-23
Start date
2024-08-08
Completion date
2025-08-31
Last updated
2025-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dysphagia, Dysphagia Rehabilitation

Keywords

post-extubation dysphagia, post-extubation laryngospasm

Brief summary

Post- extubation complications delay the complete recovery of critically ill patient. The clinical pathway is one strategies that help to manage and control these complications.

Detailed description

The presence of endotracheal tube is associated with various fatal complications which are diagnosed mainly in post- extubation time. Those complications include laryngeal edema, laryngospasm, and post-extubation dysphagia which delay the complete recovery of critically ill patient. The clinical pathway is one of the excellent strategies that help the critical care staff to manage and control these complications

Interventions

COMBINATION_PRODUCTETT cuff pressure monitoring, ETT suctioning, cough augmentation technique, swallowing exercises,: Nebulized budesonide 1mg and IV methylprednisolone 40 mg we

cough augmentation, larson maneuver, swallowing rehabilitation

Sponsors

Damanhour University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Masking description

post-extubation complications outcomes (laryngospasm, laryngeal edema and dysphagia)

Intervention model description

non- clinical pathway group and clinical pathway group

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Adult (\>18 years) * orally intubated patients for the first time attached with MV for less than two weeks * with Glasgow coma scale (GCS) from 13-15.

Exclusion criteria

* patients admitted with high risk for laryngeal edema, * difficult intubation, * ETT/anterior-posterior diameter ˃45%, * self-extubation, and * planned for tracheostomy.

Design outcomes

Primary

MeasureTime frameDescription
prevention of laryngeal edema72 hours after extubationmeasured by respiratory distress observation score that it ranges from 0-16. the high score indicates sever respiratory distress
laryngospasm72 hours after extubationmeasured by four point scale. it composed from 4 grades, grade 0 indicates no laryngospasm, grade 3 indicates severe degree of laryngospasm.
dysphagia72 hours after extubationmeasured by Gugging Swallowing Screen scale that it ranges from 0 -20. the high score indicates severe dysphagia

Countries

Egypt

Contacts

Primary Contactheba attia effect of adult intubated CP on post-extubation complications
heba.attia@nur.dmu.edu.eg045 01274855242

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026