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Role of Early API in Accurately Differentiating Hepatocellular Carcinoma From Dysplastic Nodules in Cirrhotic Patients

Role of Early Arterial Phase Imaging in Accurately Differentiating Hepatocellular Carcinoma From Dysplastic Nodules in Cirrhotic Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07080372
Enrollment
73
Registered
2025-07-23
Start date
2025-03-17
Completion date
2026-02-28
Last updated
2025-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dysplastic Nodule

Brief summary

Liver cirrhosis is a common consequence of chronic liver disease, resulting from sustained hepatic injury due to various etiologies. Cirrhosis predisposes individuals to the development of hepatocellular carcinoma (HCC), the most prevalent primary malignancy of the liver. Among cirrhotic patients, distinguishing between hepatocellular carcinoma and dysplastic nodules is crucial for timely diagnosis, treatment planning, and prognostic assessment.

Interventions

DIAGNOSTIC_TESTassesment

This study aims to assess the role of early arterial phase in detecting and differentiating hepatocellular carcinoma from dysplastic nodules in chronic liver disease patients.

Sponsors

Superior University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
5 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients with abnormal LFTs * Liver lesions of various sizes * Patients with chronic liver disease * Individuals undergoing routine liver screening * Willing participants who consent to the study

Exclusion criteria

* Children less than 5years * Patients who are allergic or have a history of allergy to contrast media * Patients with deranged renal function tests * Pregnant women

Design outcomes

Primary

MeasureTime frameDescription
self administered proforma form12 MonthsA clinical history form is a structured document used to gather comprehensive information about a patient's medical background and current health status. It typically includes sections for identifying patient demographics, past medical history, family history, social history, medications, allergies, and a detailed account of the current illness or complaint.

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026