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Healing of Corneal Incision After Cataract Surgery in Diabetic Patients

Corneal Incision Healing and Its Influencing Factors After Cataract Phacoemulsification in Diabetic Patients -- Based on Anterior Segment Optical Coherence Tomography

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT07076420
Enrollment
110
Registered
2025-07-22
Start date
2024-04-01
Completion date
2025-01-15
Last updated
2025-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract, Diabetes

Brief summary

The objective of this observational study was to understand the healing of corneal incision after cataract surgery in diabetic patients and its influencing factors. The main questions it aims to answer are: Is corneal incision healing worse in diabetic patients after cataract surgery than in non-diabetic patients? What are the factors affecting corneal incision healing after cataract surgery in diabetic patients? The results of anterior segment optical coherence tomography before and after cataract surgery in cataract patients with or without diabetes will be collected and analyzed.

Interventions

None listed

Sponsors

Zhongnan Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

Patients who experience blurred vision and painless visual acuity decline, and are diagnosed with cataract (with or without diabetes) through reliable intraocular pressure, visual acuity and slit lamp examinations, and for whom phacoemulsification of cataract can be considered.

Exclusion criteria

* Use multiple eye drops before surgery. * Complicated by other eye diseases that affect corneal healing, such as keratitis, uveitis, glaucoma, etc. * Moderate to severe dry eye. * History of eye surgery. * Moderate to severe dry eye. * Grade 5 nuclear cataract. * Severe systemic diseases (such as chronic renal failure requiring dialysis, severe neurological diseases, immune diseases), pregnancy or lactation.

Design outcomes

Primary

MeasureTime frameDescription
volume of half cornea with surgical incisionBefore surgery; 1 week after surgery; 1 month after surgery
Defect of corneal incision healing1 week after surgery; 1 month after surgeryOpening of internal orifice; Endothelial dislocation; Descemet's membrane detachment

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026