Postdural Puncture Headache, Preoperative Neutrophil-to-Lymphocyte Ratio (NLR)
Conditions
Brief summary
This study will aim to investigate whether systemic inflammatory markers-especially the neutrophil-to-lymphocyte ratio (NLR)-obtained from preoperative complete blood counts can predict the development of post-dural puncture headache (PDPH) in obstetric patients undergoing cesarean section under spinal anesthesia.
Interventions
OTHERPDPH
Observational analysis of preoperative inflammatory markers (e.g., NLR, PLR, SIRI) in relation to PDPH development following spinal anesthesia.
Sponsors
Istinye University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Women aged 18 years or older * Underwent elective or emergency cesarean section under spinal anesthesia * Had complete preoperative complete blood count (CBC) data available * No known hematological or inflammatory disease * No intraoperative complications recorded * Medical records accessible for postoperative follow-up regarding PDPH symptoms
Exclusion criteria
* Age under 18 * Absence of preoperative complete blood count data * Presence of hematologic malignancy, active infection, autoimmune disease, or immunosuppressive therapy * Platelet count \<150,000/mm³ or INR \>1.5 * Incomplete or missing medical records
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Postdural Puncture Headache (PDPH) incidence | Within 10 days postoperatively | The occurrence of PDPH symptoms within 10 days following spinal anesthesia in obstetric patients, as documented in medical records. |
Countries
Turkey (Türkiye)
Contacts
Primary Contactilke dolgun
Outcome results
None listed